As one of the two main histologic subtypes of gastric cancer (GC), diffuse-type gastric cancer (DGC) containing poorly cohesive gastric carcinoma (PCC) components has a worse prognosis and does not respond well to typical therapies. Despite the large number of studies revealing the complex pathog...
Although previous studies show that microRNAs (miRNAs) can potentially be used as diagnostic markers for epilepsy, there are very few analyses of pediatric epilepsy patients. miRNA profiles using miRNA-seq was performed on plasma samples from 14 pediatri
. Our intention here is to use the major defined signaling elements as case studies which explain how the plant signaling machinery was uncovered (Table1). The following sections will cover the discovery of metabolites that interact with key metabolic regulators including SNF1-related kinase 1 (SnR...
donut-shaped object to the right is a cell; the blue-and-yellow objects to the left are secreted immunoglobulin G antibodies. Credit: Rene Cheng/University of Washington
Lung adenocarcinoma (LUAD) is the predominant histological subtype of lung cancer and the leading cause of cancer-related mortality. Identifying effective drug targets is crucial for advancing LUAD treatment strategies. This study employed proteome-wide
Given that human cytomegalovirus (HCMV) infection can alter T cell composition,23,24 we tested donors for HCMV antibodies and DNA in serum (see STAR Methods). Compared to seronegative donors (immunoglobulin G [IgG]−/IgM−), seropositive donors (IgG+/IgM−) had elevated levels of CD8...
Subsequently, to ascertain the potential role of hepatic iron as a key contributor to the development of MASH, we investigated the liver function and pathology in mice subjected to a high-iron diet (HID). In accordance with the augmented positive area of Perls’ Blue staining observed in mice...
interfere with key capsid binding interactions. We found that the best signal to noise ratio for duplicate spots (calculated as the average intensity of positive control spots compared to the average intensity of the rest of the slide) was achieved by directly fixing cell-bound AAVs without ...
We further illustrate the immune molecule-related functions in CD. This work reveals the key role of different immune molecules in the occurrence and development of CD. Materials and methods Search strategy for CD microarray datasets A total of 73 datasets were collected from the Gene Expression ...
DNA methylation (n = 565), RNA sequencing (n = 185), and single-cell RNA sequencing data (n = 8 meningioma samples,n = 2 dura samples) of new samples reported in this manuscript have been deposited in the NCBI Gene Expression Omnibus under the accessionGSE183656. Additi...