N-linked glycosylation is one of the predominant post-translational modifications involved in a number of biological functions. Since experimental characterization of glycosites is challenging, glycosite prediction is crucial. Several predictors have been made available and report high performance. Most of...
In addition, the silkworm is an economically important insect, being a primary producer of silk, and meanwhile, as a model of Lepidoptera, the silkworm could serve as a good system for investigation of signaling and physiological functions of the CAPA peptide/receptor system. Thus, identification ...
Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cells. One of the monoclonal antibodies identified the C proteins in widely divergent species ranging from human to lizard. In all species examined, there were ... Choi,D Y. - 《...
Immunological comparisons were performed with antibodies raised against the 76.5-kDa protein. They indicated a weak relationship between the two proteins. From that we conclude that within one type of organelle, i.e., glyoxysome, two isoenzymes with multiple functions are located. 展开 ...
ARTICLE Received 9 Aug 2013 | Accepted 17 Dec 2013 | Published 24 Jan 2014 DOI: 10.1038/ncomms4139 Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations Hsing-Mao Chu1, Jon Wright1,2, Yueh-Hsuan Chan3, Chien-Jen Lin1, Tse Wen ...
biological functions other,otherIn the quest to discover new research tools and to develop better agents in the fight against cancer, two antibodies, G6 and B20-4, were isolated from synthetic antibody phage libraries. Unlike the AVASTIN antibody, a recently approved agent for the treatment of ...
[6] and because structural features of proteins generally are more conserved than their functions. Similar to the Orco structure [10], our models of ItypOR46 and ItypOR49 revealed a cleft exposed to the extracellular side. Based on its location, it is reasonable to assume that this cleft ...
We also investigated whether the Opn5B protein is co-expressed with other opsin proteins. Because these anti-opsin antibodies were all raised in rabbits, it was difficult to dually immunostain different opsins in the same sections. Therefore, we exploited the large dimension of the Type-I photore...
Supershift experiments were performed with antibodies as listed. The position of the supershifted complex is indicated by an arrow. One biological replicate of four is shown. Gt goat, IgG immunoglobulin G, NC nonspecific control (NC I: anti-STAT5A, rabbit; NC II: anti-PDX1, rabbit; NC III...
In this study, we found that the gene TALDO1 has two translational initiation sites, generating two isoforms that differ by the presence of the first 10 N-terminal amino acids. Notably, the long and short isoforms were differentially localised to the cell nucleus and cytoplasm, respectively. ...