Identification of Genes in Human Genomic DNA - Burge - 1997 () Citation Context ...e DNA Models We built Markov chains of several orders on DNA based upon 2.1 megabases of data collected to model the statistics of introns and inter-genie regions in the GENSCAN gene finding program (=-=...
they showed no differences in correct response rate or ability to read human communicative gestures. We examined gene polymorphisms in oxytocin, oxytocin receptor, melanocortin 2 receptor, and a Williams–Beuren syndrome-related gene (WBSCR17), as candidate genes of dog domestication. The single-nucl...
Identification of Novel Genes in Human Airway Epithelial Cells associated with Chronic Obstructive Pulmonary Disease (COPD) using Machine-Based Learning Algorithms Shayan Mostafaei, Anoshirvan Kazemnejad, Sadegh Azimzadeh Jamalkandi, Soroush Amirhashchi, Seamas C. Donnelly, Michelle E. Armstrong...
while their targets, genes (GROWTH REGULATING FACTORS and SQUAMOSA PROMOTER BINDING PROTEIN-LIKE genes) and lncRNAs, were down-regulated. Further, the trans-regulated targets of these lncRNAs, like wall-associated kinase2 and phosphomannose isomerase1, are involved in pollen wall...
pMEIs with high allele frequency (AF) among human populations are considered as common pMEIs. Common pMEIs that are not associated with expression of nearby genes in the tissue of interest can be considered as natural landmarks for genomic loci that can potentially harbor transgene integrations ...
genes [25]. To obtain sufficient statistical power to detect cancer driver genes with low mutation frequency, a large number of cancer patients must be sequenced [26]. This situation has provoked a number of methods that assist in identifying driver genes. Generally, these methods can be ...
- 《Human Genetics》 被引量: 56发表: 2009年 Identification of a Predominant Co-Regulation among Kinetochore Genes, Prospective Regulatory Elements, and Association with Genomic Instability The NCI-60 cell line panel is the most extensively characterized set of cells in existence, and has been used...
A multicopy suppression profiling (MSP) screen, where genes are overexpressed to identify those that confer resistance to the compound of interest was also performed [25]. The genes identified from the chemogenomic assays were individually validated to confirm their involvement in COS sensitivity or ...
11. The functions of nine enzymes from the APEXd BGC were characterized after heterologous expression and purification from E. coli and used to form APEXd in vitro. Our current study addresses outstanding questions in APE biology, including the identity of the essential genes for in vivo ...
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003;34:267–73. Article CAS PubMed Google Scholar Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a ...