Department of Molecular ReproductionSpringer-VerlagResonanceMahadevan.Oswald Avery and the identification of DNA as the genetic material.Resonance.2007 ,9:4--11.Mahadevan. Oswald Avery and the identification of DNA as the genetic material[J].Resonance,2007.4-11.doi:10.1007/s12045-007-0089-z....
was a milestone in establishing that DNA is the genetic material. However, at the time, it had little impact on scientists' view about the physical basis of inheritance. The genetic material had to encode all the information needed to specify an organism, and the chemical complexity and diversi...
was a milestone in establishing that DNA is the genetic material. However, at the time, it had little impact on scientists' view about the physical basis of inheritance. The genetic material had to encode all the information needed to specify an organism, and the chemical complexity and diversi...
Paragraph 6:In retrospect, the work of Avery, MacLeod, and McCarty, published in 1944, was a milestone in establishing that DNA is the genetic material. However, at the time, it had little impact on scientists' view about the physical basis of inheritance. The genetic material had to encode...
Optical analysis of DNA in nanochannels The optical DNA mapping of the single plasmid molecules were performed as described in ref.18. Using a combination of a DNA fluorescent dye (YOYO-1) and Netropsin, an antibiotic that binds specifically to AT DNA regions, this technique allows the acquisiti...
(a) Agarose gel electrophoresis of PCR results from ginseng samples. Lane 1–6: negative control (water was used as sample), tablet, pill, oral liquid, injection, positive control (DNA extracted from reference medical material is used as sample). Tablet and pill samples are subjected to one...
Suitable for Chinese medicinal materials which lack DNA sequence information, as they do not require prior sequence knowledge Large numbers of loci can be screened in a short time Require DNA of good quality, in terms of DNA integrity and the absence of PCR inhibitors ...
There are several studies about the genetic variation of safflower cultivars using various molecular DNA markers, such as SNP (Chapman and Burke, 2007), SRAP (Peng et al., 2008), ISSR (Chapman et al., 2009, Golkar et al., 2011), and AFLP (Zhang et al., 2009, Feng et al., 2010...
DNA methylation is a biochemical process in which the methyl group is covalently attached to the 5-position of cytosine, yielding 5-methylcytosine (5-methylcytosine, 5mC). While the majority of DNA methylation events occur at CG, other nucleotide combinations such as CHG and CHH contexts are ...
Genome-wide association studies (GWAS) have recently identified genetic loci associated with site-specific DNAm of CpGs, known as DNA methylation quantitative trait loci (meQTLs)10,11,12,13,14. We hypothesized that identifying meQTL variants and linking them to disease-associated genetic variants ...