MHC I-肽复合物表达于细胞表面:MHC I类分子必须与抗原肽结合,才能在细胞表面稳定地表达,并进一步将抗原递呈给CD8+T细胞识别。 MHC I类五聚体技术就是利用了MHC I分子在与抗原肽结合后与抗原特异性CD8+T受体(TCR)相结合,通过流式细胞术检测荧光素信号作为readout,进而可以得知特异性结合抗原肽的CD8+T细胞群的比...
MHC Class II (I-A/I-E) -KO 品系全名 C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc 目录号 NM-KO-18032 品系状态 活体 加入购物车 导出PDF 基因信息 基因名H2-Ab1 基因曾用名 IAb; Ia2; Ia-2; Abeta; H-2Ab; H2-Ab; Rmcs1; I-Abeta NCBI ID 14961 MGI ...
II antigen A, alpha; histocompatibility 2, class II antigen A, beta 1; I-Ab; I-Ad; I-Aq; I-E beta MHC class II; I-Ed; I-Ek; IAalpha; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; major histocompatibility protein class II ...
II antigen A, alpha; histocompatibility 2, class II antigen A, beta 1; I-Ab; I-Ad; I-Aq; I-E beta MHC class II; I-Ed; I-Ek; IAalpha; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; major histocompatibility protein class II ...
为了避免对T细胞的潜在影响,通过多个洗涤步骤从DC中去除recArgI,然后将它们与分离的OT-II T细胞以5:1的比例一起培养。如通过流式细胞术测得的,以30μg/ml浓度的重组精氨酸酶I处理树突细胞并未改变原型DC激活标志物CD80和MHCII的表面表达。 在共同培养DC和T细胞3天之后评估MLR的结果。图5示出了精氨酸酶I对...
MHC (主要组织相容性复合体)分为MHC I类和MHCII类分子,MHC I类分子的主要作用是与胞内 蛋白、核蛋白和病毒蛋白形成抗原-MHCI类复合物,并呈递给细胞毒性T淋巴细胞,诱发特异性细胞杀伤 效应;MHC II类分子主要表达于抗原呈递细胞(如树突状细胞、B细胞等),主要作用是以抗原-MHCII类 复合物的形式将抗...
鱼主要组织相容性复合体II类(MHCII)ELISA试剂盒 价格: ￥1800/盒 产品详情: 鱼主要组织相容性复合体II类(MHCII)ELISA试剂盒产品规格 :96T/48T 货号:FT-Y10882P 检测范围:7.5-240ng/mL 保存条件 ... 包装规格:96T 1800元/48T 1200元 用途:用于科研实验,不得用于临床 货号:FT-Y10882P 品牌:梵态 产地:...
上海玉博生物科技有限公司 主要致力于“Anti-Mouse MHC Class II I-Ad APC (AMS-32.1) ** 17-5323-82”的生产销售。多年的“Anti-Mouse MHC Class II I-Ad APC (AMS-32.1) ** 17-5323-82”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深
In more than 80% of these tumors, point mutations in IDH type 1 (IDH1) lead to expression of the tumor-specific protein IDH1R132H. IDH1R132H harbors a major histocompatibility complex class II (MHCII)-restricted neoantigen that was safely and successfully targeted in a first-in human ...
1f). These data demonstrate that TCR-MAP is a specific and sensitive system to capture cognate pMHC–TCR interactions for both class I-restricted (HLA-A2) and class II-restricted T cells in humans. TCR-MAP captures mouse MHC class I-restricted (H2-Kb) and class II-restricted (H2-IAb) ...