The Step-by-Step Process of Hydrolysis: 1. Activation: The initial step in hydrolysis is the activation of the molecule to be hydrolyzed. This often involves the transfer of a phosphate group from adenosine triphosphate (ATP) to the molecule of interest. The addition of the phosphate group pro...
19and the protein-remodeling AAA+ ATPase PCH220. Consequently, the mechanism of the RavA ATPase cycle may be unexpectedly similar to the meticulously dissected ATP hydrolysis
11, promotes BM of HJ9,12,13. BM activity of RAD54 requires ATP hydrolysis and involves the formation of higher order RAD54 oligomers on HJ-like structures12,14. RAD54 promotes BM with significantly greater efficiency than other known eukaryotic BM proteins, like BLM or RECQ113. Moreover, ...
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although any methods and materials similar or equivalent to those described herein can be used in the practice...
Hydrolysis of nucleoside triphosphates (NTPs), such as ATP or GTP, by so-called P-loop fold nucleoside triphosphatases (also known as Walker NTPases) is one of the key enzymatic reactions. P-loop NTPase domains drive the activity of rotary ATP synthases, DNA and RNA helicases, kinesins an...
Kinesins are a superfamily of motor proteins capable of moving on microtubule (MT) filaments by using the energy from ATP hydrolysis to perform diverse functions such as the transport of intracellular cargoes, responsibility of chromosome segregation during cell division, etc. [3,4,5,6,7,8,9]...
1. Introduction Hydrolysis of nucleoside triphosphates (NTPs), such as ATP or GTP, by so-called P-loop fold nucleoside triphosphatases (also known as Walker NTPases) is one of the key enzymatic reactions. P-loop NTPase domains drive the activity of rotary ATP syn- thases, DNA and RNA ...