Introduction Enantioselective Hydrolysis of Carboxylic Acid Amides Enantioselective Hydrolysis of Cyclic Amides Enantioselective Hydrolysis of Amino Acid Amides Enantioselective Hydrolysis of Hydroxy Acid Amides Enantioselective Hydrolysis of Azido Acid Amides Selective Cleavage of a C-Terminal Amide Bond Summary an...
IntroductionEnantioselective Hydrolysis of Carboxylic Acid AmidesEnantioselective Hydrolysis of Cyclic AmidesEnantioselective Hydrolysis of Amino Acid AmidesEnantioselective Hydrolysis of Hydroxy Acid AmidesEnantioselective Hydrolysis of Azido Acid AmidesSelective Cleavage of a C-Terminal Amide BondSummary and OutlookRe...
The basic hydrolysis of -disubstituted imidate salts proceeds via a hemi-orthoamide tetrahedral intermediate which can in principle give amide–alcohol or ... Pierre Deslongchamps, , Claude Lebreux, and , Roland Taillefer - 《Canadian Journal of Chemistry》 被引量: 174发表: 1973年 ...
amide formation, amide hydrolysisCareful mass spectrometric analysis of the O content of approx. 50% enriched acetanilide (2) and N-cyclohexylacetamide (3) recovered from acidic media during the course of hydrolysis reveals that both species suffer O loss. The percent of O exchange per t of ...
HYDROLYSIS OF AMIDE GROUP
Hydrolytic reactions catalyzed by both acid and base are common, for example, the hydrolysis ofamidesor esters. Their hydrolysis occurs when a nucleophile (water or a hydroxyl anion) attacks thecarbonylgroup of the ester or amide. In water, hydroxyl ions are better nucleophiles than water itself...
PURPOSE:To facilitate the hydrolysis of a glycylamide bond existing in a hydrophobic solid and stable in normal state, by converting the bond to quaternary ammonium with ethylene oxide or propylene oxide. CONSTITUTION:A glycylamide group of formula I (R1, R3, R5 are H or lower alkyl; R2 and...
Hydrolysis of amide bonds is expected as a promising technology, namely in the fields of biorefinery using proteins and chemical recycling of plastics. For the model reaction of glycylglycine hydrolysis, ZrO2 was found to work as an effective catalyst and afforded glycine in up to 97%-C under ...
The release of aromatic amines from drugs and other xenobiotics resulting from the hydrolysis of metabolically labile amide bonds presents a safety risk through several mechanisms, including geno-, hepato- and nephrotoxicity. Whilst multiple in vitro sys
lysergamide((5R,8R)-9,10-didehydro-6-methyler- goline-8b-carboxamide,1a,Fig.1)byabacterial amidasewasnotreportedtoourknowledge.Hy- drolysisoflysergamidebythefungusCla6iceps purpureawasdescribedinapatent(Amicietal., 1964)butthemethodishardlyreproducibleas ...