Proteins fold into unique three-dimensional structures in aqueous or lipid environments. The conformation of folded proteins is stabilized by non-bonded interactions among main and side chains of polypeptides. In addition to the intramolecular interactions within polypeptide, hydration water molecules ...
polypeptides. In the small intestine they are acted on by the pancreatic enzymes trypsin, chymotrypsin, and carboxypeptidase to form polypeptides and amino acids. In the small intestine the peptidases complete the breakdown of the peptides into dipeptides and amino acids. Almost all proteins are ...
Self-association of collagen triple helix peptides into higher order structures Interest in self-association of peptides and proteins is motivated by an interest in the mechanism of physiologically higher order assembly of proteins suc... K Kar,P Amin,MA Bryan,... - 《Journal of Biological Chem...
proteinsFirst page of articledoi:10.1002/bip.1967.360050311D. PuettJohn Wiley & Sons, Ltd.BiopolymersD. Puett ""DTA and heats of hydration of some polypeptides"", Biopolymers , vol. 5, pp.327 -329 1967D. Puett, Biopolymers, 5 , 327 (1967)....
Interaction models for water in relation to protein hydration For molecular dynamics simulations of hydrated proteins a simple yet reliable model for the i... Successive parameterizations of the GROMOS force field have been used successfully to simulate biomolecular systems over a long period of time....
assembling of virus capsid proteins12, and in the biogenesis and fission of droplets in the endoplasmic reticulum13. Recently, membranes have been reported to control the size of intracellular condensates and modify their material properties14. Furthermore, the crosstalk between membranes and condensates...
The ROA spectra of all three are dominated by signatures of helical elements in the major coat proteins, as expected from pre-existing data. The helical elements generate strong sharp positive ROA bands at ∼1300 and 1342 cm−1 in H2O solution, but in 2H2O solution the ∼1342 cm−1...
assembling of virus capsid proteins12, and in the biogenesis and fission of droplets in the endoplasmic reticulum13. Recently, membranes have been reported to control the size of intracellular condensates and modify their material properties14. Furthermore, the crosstalk between membranes and condensates...
The interactions of water molecules with proteins have been of interest for a long time. This stems from the role of water in protein folding, during which apolar side-chains tend to be buried in the centre of the protein (thus reducing their contact with aqueous solvent). On folding, intra...
(i) we are able to simultaneously determine the excess partial quantities of water and proteins; (ii) these thermodynamic quantities can be determined in the entire range of water content. Here, in particular, the excess partial enthalpies of water and bovine pancreatic ribonuclease A (RNase A)...