The |3-barrel shaped polypeptide transporter, an old concept for precursor protein transfer across membranes Proteins are translocated across or inserted into membranes by machines that are composed of soluble and membrane-anchored subunits. The molecular action o... W Löffelhardt,AV Haeseler,E Sc...
Polypeptide Protein Drug Liposome 多肽蛋白质药物脂质体Liposomes are artificial membrane vesicles which can be used as either passive or active targeted drug carrier systems. In polypeptide and protein drug- delivery systems, liposomes have some unique therapeutic advantages, such as the ability to ...
Post-translational modifications (PTMs) regulate various aspects of protein function, including degradation. Mass spectrometric methods relying on pulsed metabolic labeling are popular to quantify turnover rates on a proteome-wide scale. Such data have t
polypeptides joined together. Hence, proteins essentially are very large peptides. In fact, some researchers use the termpeptideto refer specifically to oligopeptides, or otherwise relatively short amino acid chains, with the termpolypeptidebeing used to describe proteins, or chains of 50 or more ...
Nanopores are single-molecule sensors used in nucleic acid analysis, whereas their applicability towards full protein identification has yet to be demonstrated. Here, we show that an engineered Fragaceatoxin C nanopore is capable of identifying individua
帮助Aminoandamino氨基酸蛋白质Acidsacids 系统标签: aminoacidsproteinspeptides氨基酸蛋白质 1AminoAcids,PeptidesandProteinsAminoAcids,PeptidesandProteinsTheAminoAcidsinProteinsPolypeptidesandProteinsProteinFunctionProteinSize,CompositionandPropertiesFourLevelsofProteinStructureProteinPrimaryStructureChromatographyandElectrophoresis...
2. Protein hydrolysates and biologically active peptides as food preservatives added directly to the product 3. Biodegradable, edible coatings with the addition of protein hydrolysates and biologically active peptides as packaging materials 4. Encapsulated biopeptides and protein hydrolysates as active com...
neuropeptide Y, peptide YY, and pancreatic polypeptide); opioid peptides (e.g. proopiomelanocortin, enkephalin pentapeptides, and prodynorphin); calcitonin peptides (e.g. calcitonin and amylin); and self-assembling peptides (e.g. aromatic short peptides, biomimetic, peptide amphiphiles and, pepti...
attractive therapeutic targets, but preparative methods to access amidated pharmaceuticals are limited both on lab and manufacturing-scale. Here, the authors report a straightforward and scalable approach to the C-terminal α-amidation of peptides and proteins from cysteine-extended polypeptide precursors....
tetrazines, phosphines, etc.) that exhibit minimal or no cross-reactivity with the functionalities found within the 21 proteinogenic amino acids. While some of these reactions can suffer from sluggish kinetics, and in most cases leave a large non-natural scar between the peptide backbone and ...