protein, polypeptide and peptide hormonesdoi:10.1016/S0300-9084(76)80210-6MichelR.Elsevier Masson SASBiochimie
Post-translational modifications (PTMs) regulate various aspects of protein function, including degradation. Mass spectrometric methods relying on pulsed metabolic labeling are popular to quantify turnover rates on a proteome-wide scale. Such data have traditionally been interpreted in the context of prot...
Peptides and proteins are widely used to treat a range of medical conditions; however, they often have to be injected and their effects are short-lived. These shortcomings of the native structure can be addressed by molecular engineering, but this is a c
Crotamine also called as myoneurotoxin is found in the venom ofCrotalus durissus terrificus,a South American snake and is a major constituent of its venom [86]. The composition of this polypeptide includes 42 amino acids, 3 disulfide bonds stabilizing the structure with 2 α-helices and 2 ß...
Peptide tyrosine tyrosine (PYY) was originally isolated from porcine gut, which exhibits striking sequence homology with members of the pancreatic polypeptide family, including neuropeptide tyrosine (NPY). The peptide is localized to enteroglucagon containing (L/EG) and pancreatic (A) cells in many ...
Caeruloplasmin is a copper binding plasma glycoprotein consisting of a single polypeptide chain. It has a molecular weight of 132kDa and occurs in plasma at a concentration of 150-500 mg/L. Although the physiological functions of Caeruloplasmin are not fully understood it is implicated in a nu...
Vasoactive intestinal peptide(VIP) is a 28aminoacid peptide withsequence homologyand biological similarities tosecretin, growth hormone-releasing hormone (GHRH),gastric inhibitory polypeptide,glucagon(1), andhelodermin(2). TheVIPgene also encodespeptide histidine isoleucine(PHI) which shows a 9amino aci...
NTL has a molecular weight of 26 kDa, and is probably a dimer with two identical subunits. NTL protein, predicted by cDNA sequence, contains a mature polypeptide and a C-terminal peptide extension [80]. Moreover, NTL primary polypeptide contains three subdomains, each with a conserved mannose...
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