早年衰老综合症(Hutchinson-Gilford Progeria syndrome),简称早衰症。1886年Hutchinson首例报道,1897年Guilford进一步描述,所以也称Hutchinson-Gilford综合征.后来文献中称为HGPS.流行病学调查显示,美国本病的发病率为1/800万,男女之比为1.5:1,97%为白色人种.早衰症是一种极端罕见的先天遗传性疾病,其患者身体的老化过程...
必应词典为您提供Hutchinson-Gilford-Syndrome的释义,网络释义: 早老症;早衰症;吉福德氏综合症;
疾病中文名:早老症 疾病英文名:Hutchinson Gilford progeria syndrome 别名:progeria 患病率:<1 / 1 000 000 遗传方式:常染色体显性 病因 Progeria(早老症)患者在儿童时期会有提早老化的现象发生,又称为Hutchinson - Gilford progeria syndrome。早老症最早是在...
Hutchinson-Gilford Syndrome (progeria, HGPS)A rare very precocious aging of either recessive or dominant inheritance (human chromosome 1q) leading to heart defects and death by the second decade of life. The disease is usually accompanied by multiple heat-labile protein defects. The basic defect ...
syndrome 英[ˈsɪndrəʊm] 美 [ˈsɪndroʊm] 释义n. [临床] 综合征;综合症状;并发症状;校验子;并发位 例句Furthermore, regular monitoring of the organisms causing each syndrome should be conducted on a regular basis to validate the treatment recommendations.此外,应定期对引起每种...
(redirected from Hutchinson Gilford Progeria Syndrome)Also found in: Thesaurus, Medical, Encyclopedia. pro·ger·i·a (prō-jîr′ē-ə) n. A rare genetic disorder of childhood that is characterized by rapid onset of the physical changes typical of old age, usually resulting in death ...
Progeria(Hutchinson-Gilford Syndrome)早衰症 Othernames:-Hutchinson–Gilfordprogeriasyndrome,Hutchinson–Gilfordsyndrome Definition:Hutchinson-Gilfordprogeriasyndromeisagenetic conditioncharacterizedbythedramatic,rapidappearanceofagingbeginninginchildhood.Affectedchildrentypicallylooknormalatbirthandinearlyinfancy,but...
Hutchinson-Gilford Progeria Syndrome: Challenges at Bench and BedsideCalcitriolHGPSHutchinson Gilford progeria syndromeLaminsPremature ageingProgerinRetinoidsThe structural nuclear proteins known as "lamins" (A-type and B-type) provide a scaffold for the compartmentalization of genome function that is ...
Progeria, also known as Hutchinson-Gilford progeria syndrome (HGPS), is a rare genetic condition that results in a child's body aging rapidly. A mutation in the LMNA gene causes it to make an abnormal protein. When cells use this protein, called progerin, they break down more easily, whic...
Hutchinson-Gilford progeria syndrome also causes hair loss (alopecia), aged-looking skin, joint abnormalities, and a loss of fat under the skin (subcutaneous fat). This condition does not affect intellectual development or the development of motor skills such as sitting, standing, and walking....