参考文献 [1] Piekarowicz K, Machowska M, Dzianisava V, Rzepecki R. Hutchinson-Gilford Progeria Syndrome-Current Status and Prospects for Gene Therapy Treatment. Cells. 2019;8(2):88. Published 2019 Jan 25. doi:10.3390/cells80...
疾病中文名:早老症 疾病英文名:Hutchinson Gilford progeria syndrome 别名:progeria 患病率:<1 / 1 000 000 遗传方式:常染色体显性 病因 Progeria(早老症)患者在儿童时期会有提早老化的现象发生,又称为Hutchinson - Gilford progeria syndrome。早老症最早是在...
× 儿童早老症(Hutchinson-Gilford progeria syndrome,HGPS)是一种罕见的出生早期出现过早老化,并可累及皮肤、脂肪、心血管、骨骼等多器官系统的遗传性疾病。除机体衰老之外,HGPS患者不表现正常衰老的其他特征,如易发生癌症及痴呆等。本病极为罕见,发病率约为1∶8 000 000～1∶4 000 000。多数患儿仅能活到6～20...
syndrome 英[ˈsɪndrəʊm] 美 [ˈsɪndroʊm] 释义n. [临床] 综合征;综合症状;并发症状;校验子;并发位 例句Furthermore, regular monitoring of the organisms causing each syndrome should be conducted on a regular basis to validate the treatment recommendations.此外,应定期对引起每种...
2021 年 1 月 6 日,哈佛大学化学与化学生物学系的David R. Liu教授在Nature上在线发表了题为 In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice 的研究成果。 该研究构建了一种腺嘌呤碱基编辑器(ABE),在无需断裂双链 DNA 的情况下,可将 LMNA 中 A・T 碱基对转化为 G・C 碱...
Progeria(Hutchinson-GilfordSyndrome)早衰症 Othernames:-Hutchinson–Gilfordprogeriasyndrome,Hutchinson–Gilfordsyndrome Definition:Hutchinson-Gilfordprogeriasyndromeisagenetic conditioncharacterizedbythedramatic,rapidappearanceofagingbeginninginchildhood.Affectedchildrentypicallylooknormalatbirthandinearlyinfancy,butthengrowmore...
1、Other names :- HutchinsonGilford progeria syndrome, HutchinsonGilford syndromeDefinition:Hutchinson-Gilford progeria syndrome is a genetic condition characterized by the dramatic, rapid appearance of aging beginning in childhood. Affected children typically look normal at birth and in early infancy, 2、...
Hutchinson-Gilford Syndrome (progeria, HGPS)A rare very precocious aging of either recessive or dominant inheritance (human chromosome 1q) leading to heart defects and death by the second decade of life. The disease is usually accompanied by multiple heat-labile protein defects. The basic defect ...
Thesaurus Medical Encyclopedia pro·ger·i·a (prō-jîr′ē-ə) n. Araregeneticdisorderofchildhoodthatischaracterizedbyrapidonsetofthephysicalchangestypicalofoldage,usuallyresultingindeathbeforetheageof20.AlsocalledHutchinson-Gilfordprogeriasyndrome. ...
必应词典为您提供Hutchinson-Gilford-Syndrome的释义,网络释义: 早老症;早衰症;吉福德氏综合症;