Synonyms Laminopathies; Progeria Definition Hutchinson-Gilford progeria syndrome (HGPS), often referred to as progeria, is an extremely rare autosomal dominant neonatal condition. Children with HGPS have a small stature, distinctive facial features and rapid aging in many organ systems. Progeria is a...
BACKGROUND Hutchinson-Gilford progeria syndrome (HGPS), also known as progeria, is due to a mutation in the LMNA gene, resulting in a life expectancy of no more than 13 years, and a high mortality rate due to cardiovascular disease. We report the case of a 13-year-old boy from Thailand...
Hutchinson- Gilford progeria syndrome is a type of progeroid syndrome, characterised by abnormal facies, bone abnormalities, sclerodermatous skin changes and retarded physical development. Average life expectancy of progeria patients is 13 years. Herein we are reporting a case of progeria who is 21 ...
Genetics Tipping the Balance of Double-Strand Break Repair in Cells Modeling Hutchinson-Gilford Progeria Syndrome UNIVERSITY OF SOUTH CAROLINA Alan Waldman PatrickAndrew RobertHutchinson-Gilford Progeria Syndrome is disease of highly accelerated aging. In addition to appearing physically old mere months ...
Hutchinson-Gilford progeriaacute coronary syndromeinterventional cardiac catheterizationstent implantationrevascularizationATHEROSCLEROSISFEATURESHutchinson鈥揋ilford progeria syndrome is an extremely rare genetic disease caused by a de novo mutation in the LMNA gene, leading to an accumulation of a form of Lamin...
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder caused by the synthesis of progerin, which is noted for accelerated aging and CVD. This mutant form of prelamin A induces generalised atherosclerosis, vascular calcification, and cardiac electrophysiological abnormalities, leading to ...
A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome. J Clin Bioinform 2013;3:2Arancio W,Giordano C,Pizzolanti G.A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome[J].J Clin Bioinforma,2013,3(1):2....
Epigenetic involvement in hutchinson-gilford progeria syndrome: a mini-review. Gerontology 2014;60:197-203.Arancio W, Pizzolanti G, Genovese SI, Pitrone M and Giordano C: Epigenetic involvement in Hutchinson‑Gilford progeria syndrome: A mini‑review. Gerontology 60: 197‑203, ...