Tumor necrosis factor;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a;Tumor necrosis factor, membrane form;N-terminal fragment;NTF;Intracellular domain 1;ICD1;Intracellular domain 2;ICD2;C-domain 1;C-domain 2;Tumor necrosis factor, soluble form;TNF;TNFA, TNFSF2; TNF...
14). On gene expression analysis, the TNFa signaling via NFkB pathway, which plays a role in enhancing costimulatory signaling to the T cells [37], was particularly associated with the IPI+ context (Fig. 5C). Exhaustion markers such as TIGIT, LAG3 and HAVCR2 were most notable in the DN...
(B) Semiquantitative analysis was performed by measuring the density of the dots and revealed differential secretion patterns of different cytokines (Adiponectin; Apolipoprotein; CD147; IL-8; Lipocalin; MMP-9; CXCL4; CD31) in response to leptin, TNFa and hypoxia treatment compared to the internal...
Using a total of 24 combinations of primers, we isolated 21 differentially expressed amplified nucleotide products that were induced by TNFa or TNFa/CHX, but not CHX alone, from two separate preparations of RNA. These differentially expressed products were then further amplified and used as probes...
(IL4R) Tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) Tumor necrosis factor receptor superfamily, member 21 (TNFRSF21) Apoptosis inhibitor 5 (API5) 0 1 2 3 4 5 Fold Increased Expression 6 7 89 Up Down Figure 4 Differential expression of apoptosis-related genes in PGC-1α-...
Walker, T., Adamson, A. & Jackson, D. A. BCL-3 attenuation of TNFA expression involves an incoherent feed-forward loop regulated by chromatin structure.PLoS One8, e77015,https://doi.org/10.1371/journal.pone.0077015(2013). ArticleADSCASPubMedPubMed CentralGoogle Scholar ...
Regarding TNF signaling, TNF receptor TNFRSF1A as well as the TNF target gene TNFAIP3 were expressed by epithelial cells (Supplementary Fig. 7a), preferentially within differentiated colonocyte populations, including inflammatory colonocytes, in addition to secretory progenitors (Supplementary Fig. 7a)...
CST 4625S A20/TNFAIP3 Antibody 100µl ￥3,100 NF-kB Signaling Polyclonal Antibody -20C CST 4627S β-Catenin (L54E2) Mouse mAb (Alexa Fluor® 647 Conjugate) 100µl ￥3,986 Development Monoclonal Antibody 4C CST 4628S TMS1 Antibody 100µl ￥3,100 Apoptosis Polyclonal Antibody -20C...
It turned out that 5 genes were jointly up-regulated in preadipocytes as well as in adipocytes (tumor necrosis factor alpha-induced protein 3 (TNFAIP3), chemokine C-C motif ligand 20 (CCL-20), interleukin 6 (IL-6), interleukin 8 (IL-8) and monocyte chemoattractant protein 1 (MCP-1))...
8a–c). One of the NRF2 targets is TNFAIP3 (A20) which is a negative regulator of the NF-κB pathway and macrophage activation18. We measured A20 expression in iMACs and found that it decreased in ACOD1-/- iMACs (Supplementary Fig. 8d), which is likely to mediate increased NF-κB ...