The Human Protein Atlas (HPA) project is a large-scale initiative aiming at mapping the entire human proteome using antibody-based proteomics and integration of various other omics technologies. The publicly available knowledge resource www.proteinatlas.org is one of the world's most visited ...
The Human Protein Atlas as a proteomic resource for biomarker discovery The Human Protein Atlas project was launched in 2003 with the aim of creating a map of protein expression patterns in normal cells, tissues and cancer... F Pontén,JM Schwenk,A Asplund,... - 《Journal of Internal Medici...
The protein atlas team first uses the human genome – the sequence of all the 20000 or so genes in human cells – to encode individual proteins. They then develop 'antibodies' – protein molecules that recognise specific targets – against each of these proteins. The antibody that recognises a...
Inaugurated in 2018, the Human BioMolecular Atlas Program (HuBMAP) endeavours to construct comprehensive spatial maps that feature a range of biomolecules such as RNA, proteins, and metabolites in human organs at single-cell resolution. This collection features the research, datasets, methods and ...
Nestin is an endothelial-enriched protein in healthy human adult tissuesWe performed RNAseq tissue transcript profiling of 176 samples collected from 37 adult human organs (Table S1) as part of the Human Protein Atlas Project, version 17 (HPA; www.proteinatlas.org)...
while the whiskers extend from min to max values. Points are displayed as outliers if they are above or below 1.5 times the interquartile range.eUnsupervised clustering of normalized expression (Log2nTPM) of the indicated genes in the indicated tissues (data from The Human Protein Atlas v21.0...
A collection of research articles and related content from the Human BioMolecular Atlas Program describing the distribution of biomolecules across single cells, tissues and organs in the human body.
As an example, The Human Microbiome Project (HMP) defines the human microbiome as the collection of all the microorganisms, including eukaryotes, archaea, bacteria, and viruses, living in association with the human body. From:Theriogenology,2022 ...
Pinpointing subcellular protein localizations from microscopy images is easy to the trained eye, but challenging to automate. Based on the Human Protein Atlas image collection, we held a competition to identify deep learning solutions to solve this task.
12 The Genotype-Tissue Expression Project (GTEx),13 and the Human Protein Atlas (HPA)5 has been recently published as two independent and comprehensive RNA-seq data sources on 30 human tissues. In HPA study, one of the major conclusion of the paper was that the largest fraction of the ...