The level of protein expression in given cells is summarized using a colour code: red, strong; orange, moderate; yellow, weak; and white, negative The Human Protein Atlas portal Within the HPA programme, 20 new antibodies are processed every day, and of those approximately 50% are approved ...
Arvinas press release:http://ir.arvinas.com/news-releases/news-release-details/arvinas-present-preclinical-tau-directed-protacr-protein The Human Protein Atlas:https://www.proteinatlas.org/ About this article Cite this article Schapira, M., Calabrese, M.F., Bullock, A.N.et al.Targeted prote...
The lung contains numerous specialized cell types with distinct roles in tissue function and integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a comprehensive topographic atlas of early human lung development. Her
The Human Proteome Organization (HUPO) launched the Human Proteome Project (HPP) in 2010, creating an international framework for global collaboration, data sharing, quality assurance and enhancing accurate annotation of the genome-encoded proteome. During the subsequent decade, the HPP established collab...
Article https://doi.org/10.1038/s41467-024-49236-7 Cell atlas of the regenerating human liver after portal vein embolization Received: 22 May 2023 Accepted: 28 May 2024 Check for updates Agnieska Brazovskaja 1,10, Tomás Gomes2,10 , Rene Holtackers2, Philipp Wahle 2, Christiane Körner ...
Protein–protein interactions (PPIs) are a central type of molecular interactions in the cell which collectively form the interactome network. Significant progress has been made toward mapping interactome networks for several species including human1,2. These networks have been highly successful in provid...
Advances in human B cell phenotypic profiling. Front. Immunol. 3, 302 (2012). Article PubMed PubMed Central Google Scholar Hay, S. B., Ferchen, K., Chetal, K., Grimes, H. L. & Salomonis, N. The Human Cell Atlas bone marrow single-cell interactive web portal. Exp. Hematol. ...
We extend this concept to identify cell types of origin using the Tabula Sapiens transcriptomic cell atlas as well as individual tissue transcriptomic cell atlases in combination with the Human Protein Atlas RNA consensus dataset. We define cell type signature scores, which allow the inference of ...
atlas of 28 health tissues21, (iv) immune cell counts (hemograms) of blood from 25 HNSCC patients, (v) RNASeq data of tumors from a 500 HNSCC patient-cohort (TCGA), (vi) RNASeq data of tumors from a 428 HNSCC patient-cohort (TCGA), (vii) proteomic data from 22 human PBMC ...
b, Subcellular localization predictions for a selection of uncharacterized human proteins for which no confident prediction could be made in BioPlex 1.0. Where possible, the figure indicates whether predicted localization is consistent with the Human Protein Atlas21. c–j, Sub-networks highlighting ...