Arvinas press release:http://ir.arvinas.com/news-releases/news-release-details/arvinas-present-preclinical-tau-directed-protacr-protein The Human Protein Atlas:https://www.proteinatlas.org/ About this article Cite this article Schapira, M., Calabrese, M.F., Bullock, A.N.et al.Targeted prote...
The Human Proteome Organization (HUPO) launched the Human Proteome Project (HPP) in 2010, creating an international framework for global collaboration, data sharing, quality assurance and enhancing accurate annotation of the genome-encoded proteome. During the subsequent decade, the HPP established collab...
and tissue specificity of each DCB, as annotated in the Human Protein Atlas (version 18.1), is indicated on the left side of the heatmap. Gene expression values in reads per million (RPM) are represented by the purple gradient and are scaled for visualization purposes. Darkness...
The Human Protein Atlas (HPA: https://www.proteinatlas.org/) was utilized for further exploration about the protein levels of model genes47,48. Additionally, the HPA was also utilized to exhibit the cellular localization on the basis of immunofluorescence. Results Identification of metabolic ...
Protein–protein interactions (PPIs) are a central type of molecular interactions in the cell which collectively form the interactome network. Significant progress has been made toward mapping interactome networks for several species including human1,2. These networks have been highly successful in provid...
A guide to the Human Protein Atlas Updated: 21 October 2019 09:23 Sitting at the lab desk in the late hour of my day, I navigate the web scrolling pages and pages of content to find the information I need to plan my next experiment: which tissue is my protein expressed in? I ...
The Human Protein Atlas Phase III trial of fostemsavir PowerPoint slides PowerPoint slide for Fig. 1 PowerPoint slide for Fig. 2 PowerPoint slide for Fig. 3 PowerPoint slide for Fig. 4 PowerPoint slide for Fig. 5 PowerPoint slide for Fig. 6 PowerPoint slide for Fig. 7 PowerPoint slide ...
Analysis of the HuRI-III protein-protein interaction network We downloaded HuRI-III from the Human interactome atlas (http://www.interactome-atlas.org/). Next, we considered all L1 metapaths containing a GEN metanode, keeping the dataset with higher coverage for each metapath and discarding thos...
We extend this concept to identify cell types of origin using the Tabula Sapiens transcriptomic cell atlas as well as individual tissue transcriptomic cell atlases in combination with the Human Protein Atlas RNA consensus dataset. We define cell type signature scores, which allow the inference of ...
Here, using droplet- and plate-based single-cell RNA sequencing of approximately 75,000 human cells across all lung tissue compartments and circulating blood, combined with a multi-pronged cell annotation approach, we create an extensive cell atlas of the human lung. We define the gene expression...