In this paper we present the design and analysis of the results from the competition Human Protein Atlas – Single-Cell Classification hosted on the Kaggle platform (https://www.kaggle.com/c/hpa-single-cell-image-classification). Given images, image-level labels and pretrained segmentation models...
Nature Reviews Genetics volume 23, pages 395–410 (2022)Cite this article 25k Accesses 108 Altmetric Metrics details Abstract The development of single-cell and spatial transcriptomics methods was instrumental in the conception of the Human Cell Atlas initiative, which aims to generate an integrated ...
Cite this article Ouyang, W., Winsnes, C.F., Hjelmare, M.et al.Analysis of the Human Protein Atlas Image Classification competition.Nat Methods16, 1254–1261 (2019). https://doi.org/10.1038/s41592-019-0658-6 Download citation Received30 April 2019 ...
Nature volume 558, pages 73–79 (2018)Cite this article 75k Accesses 581 Altmetric Metrics details Abstract Although plasma proteins have important roles in biological processes and are the direct targets of many drugs, the genetic factors that control inter-individual variation in plasma protein leve...
12 The Genotype-Tissue Expression Project (GTEx),13 and the Human Protein Atlas (HPA)5 has been recently published as two independent and comprehensive RNA-seq data sources on 30 human tissues. In HPA study, one of the major conclusion of the paper was that the largest fraction of the ...
This was further filtered for putative secreted protein-coding genes using the Human Protein Atlas as a reference. Gene–gene co-occurrence and epicardial gene module constructionCells annotated as epicardium after clustering were isolated in a new matrix, and a set of epicardial features for ...
Experimental & Molecular Medicine volume 52, pages 1443–1451 (2020)Cite this article 8897 Accesses 19 Citations 16 Altmetric Metrics details Abstract In modern biology, the correct identification of cell types is required for the developmental study of tissues and organs and the production of ...
Scientific Reports volume 11, Article number: 190 (2021) Cite this article 2482 Accesses 6 Citations 1 Altmetric Metrics details Abstract Host–pathogen interaction is one of the most powerful determinants involved in coevolutionary processes covering a broad range of biological phenomena at molecular,...
We defined genes likely to be expressed in many tissues as those having an expression level above the median for a given tissue in more than half of the tissues in the Human Protein Atlas (https://www.proteinatlas.org/). To compare the enrichment of genes defined as highly pleiotropic in...
of 162 immune-related proteins, including proteins involving the above GO categories, further demonstrated both common and distinctive expression patterns involving k2 and k3, with a number of the proteins being expressed specifically in immune-related tissues according to Human Protein Atlas14 (Fig. ...