In this paper we present the design and analysis of the results from the competition Human Protein Atlas – Single-Cell Classification hosted on the Kaggle platform (https://www.kaggle.com/c/hpa-single-cell-image-classification). Given images, image-level labels and pretrained segmentation models...
Cite this article Ouyang, W., Winsnes, C.F., Hjelmare, M.et al.Analysis of the Human Protein Atlas Image Classification competition.Nat Methods16, 1254–1261 (2019). https://doi.org/10.1038/s41592-019-0658-6 Download citation Received30 April 2019 ...
Cite this article Madissoon, E., Oliver, A.J., Kleshchevnikov, V. et al. A spatially resolved atlas of the human lung characterizes a gland-associated immune niche. Nat Genet 55, 66–77 (2023). https://doi.org/10.1038/s41588-022-01243-4 Download citation Received26 July 2022 Accepted...
The HPP Ab Resource Pillar, ostensibly led by the Human Protein Atlas (HPA; www.proteinatlas.org), was initiated in 2003 and uses Ab-based strategies to analyse spatio-temporal aspects of the proteome39. Linking the identification of proteins with ‘real-time’ localization at tissue, cell and...
To the Editor: We report on the launch of version 7 of the Human Protein Atlas with subcellular localization data and expression data for all major human tissues and organs. A milestone has been achieved with the inclusion of expression data for >50% of the human protein-coding genes. The ...
Single-cell and single-nucleus skeletal muscle aging atlas To gain a comprehensive view of human skeletal muscle aging, we profiled the transcriptomes of 90,902 cells and 92,259 nuclei from intercostal muscle biopsies of 8 young (approximately 20–40 years old) and 9 aged (approximately 60–...
Nature volume 558, pages 73–79 (2018)Cite this article 76k Accesses 581 Altmetric Metrics details Abstract Although plasma proteins have important roles in biological processes and are the direct targets of many drugs, the genetic factors that control inter-individual variation in plasma protein lev...
Nature Reviews Genetics volume 23, pages 395–410 (2022)Cite this article 25k Accesses 81 Citations 114 Altmetric Metrics details Abstract The development of single-cell and spatial transcriptomics methods was instrumental in the conception of the Human Cell Atlas initiative, which aims to generate ...
12 The Genotype-Tissue Expression Project (GTEx),13 and the Human Protein Atlas (HPA)5 has been recently published as two independent and comprehensive RNA-seq data sources on 30 human tissues. In HPA study, one of the major conclusion of the paper was that the largest fraction of the ...
Scientific Reports volume 11, Article number: 190 (2021) Cite this article 2716 Accesses 8 Citations 1 Altmetric Metrics details Abstract Host–pathogen interaction is one of the most powerful determinants involved in coevolutionary processes covering a broad range of biological phenomena at molecular,...