Human adipose tissue macrophages: M1 and M2 cell surface markers in subcutaneous and omental depots and after weight loss. J Clin Endocrinol Metab 2009;94: 4619 -23Aron-Wisnewsky J, Tordjman J, Poitou C et al (
巨噬细胞分为具有炎症和吞噬特性的经典活化巨噬细胞(M1)和具有抗炎和组织重塑和修复活性的活化巨噬细胞(M2)。关于子宫腺肌病中巨噬细胞活化的数据很少。一项研究用子宫腺肌病患者子宫的正位子宫内膜细胞与巨噬细胞共培养,与无病子宫的子宫内膜细胞相比,显示出向M2表型的改变。然而,在与巨噬细胞体外共培养后,两种...
Geelhaar-Karsch A, Schinnerling K, Conrad K, Friebel J, Allers K, Schneider T, et al. Evaluation of arginine metabolism for the analysis of M1/M2 macrophage activation in human clinical specimens . Inflamm Res (2013) 62 ( 9 ):865–910.1007/s00011-013-0642-z [ Cross Ref ]...
Levels of E-series resolvins and AA-derived LX were also higher in M2 vs. M1 (Fig. 2b, Supplementary Tables 1 and 2). This contrasts the M1 macrophage LM profile where PG, especially PGE2, and LTB4 clearly dominated the M1 phenotype (Fig. 2b)....
Furthermore, IL-34 induced the expression of CD206 and IL-10, which are M2 macrophage markers, in an in vitro assay. Our results suggest that a reduction in epidermal IL-34 in aged skin may skew the M1/M2 balance in the dermis and lead to low-grade chronic inflammation and inflammaging...
英文别名: LEGENDplex Human M1/M2 Macrophage Panel (10-plex) with Filter Plate中文名: 中文别名: CBNumber: CB715373761 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 LEGENDplex Human M1/M2 Macrophage Panel (10-plex) with Filter Plate化学性质...
M1, M2 macrophage phenotypes, tumor-associated macrophages, and two types of myeloid-derived suppressor cells were identified using documented markers from previous studies. Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article...
(excel at cross- presentation) XCR1 or CLEC9A + cDC2s CD1c + or SIRPα + M1-like CD86 + or CD80 + or iNOS + M2-like CD163 + or CD206 + B Cells CD19 + Naïve IgD + and CD27 – SwitchedMemory Ig D – and CD27 + Unswitched IgD + and CD27 + Activated CD83 + ...
2013; Human placental mesenchymal stem cells (pMSCs) play a role as immune suppressive cells by shifting macrophage differ- entiation from inflammatory M1 to anti-inflammatory M2 macrophages. Stem Cell Rev 9: 620-641.Abumaree MH,Al Jumah MA,Kalionis B,et al.Human placental mesenchymal stem ...
In conclusion, PS-NPs activated the ROS/JAK/STAT pathway, aggravated LPS-induced lung M1/M2 macrophage imbalance and promoted inflammatory responses. Our results enrich the toxic effects and related molecular mechanisms of NPs-induced lung inflammation, and provide new insights into the toxic effects...