由日本iPSC领域的大牛2019年发表在Physiological Reviews上的一篇综述:诱导多能干细胞及其在人类疾病和发育模型中的应用,系统性地梳理了从iPSC的起源到前沿应用的一系列重要事件,是入门了解诱导多能干细胞领域不可不读的文章 Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development |...
Microglia are crucial mediators of brain development and homeostasis. In recent years, it has been additionally suggested that modulation of microglial function may prove to be a useful therapeutic technique in many neurological contexts. However, before we can develop therapeutics, we need to better ...
ACTA activin A, AFE anterior foregut endoderm, DE definitive endoderm, hiPSC human induced pluripotent stem cells, VBP vocal fold basal progenitors. Source data provided as a Source Data file Full size image Simultaneously, we subjected DE and AFE cell populations to sorting to confirm presence of...
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In this study, a human induced pluripotent stem cell derived-cardiomyocyte (hiPSC-CM)-based platform for modeling ischemia–reperfusion was developed utilizing a system enabling precise control over oxygen concentration and real-time monitoring of the oxygen dynamics as well as iPS-CM functionality. ...
英文名称:iPS Human Induced Pluripotent Stem Cells 英文同义词:iPS Human Induced Pluripotent Stem Cells CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览iPS Human Induced Pluripotent Stem Cells国外供应商中国供应商 iPS Human Induced Pluripotent Stem Cells推荐供应商 ...
Despite a substantial appreciation for the critical role of macrophages in cardiometabolic diseases, understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies. Human induced pluripotent stem cell (iPSC)-derived macrophages (IP...
Mesenchymal stem cells(MSCs) derived from human induced pluripotent stem cells(hiPSCs) provide a novel source for generating adipocytes, thus opening new avenues for fundamental research and clinical medicine. We present the adipogenic potential of hiPSCs and the various methods to derive hiPSC-MSCs. ...
The development of human induced pluripotent stem cell (iPSC) models has greatly enhanced our ability to model disease in human cells. Methods have recently been improved, including increasing reprogramming efficiency, introducing non-viral and non-integrating methods of cell reprogramming, and using ...
Stroke is a major cause of permanent neurologic damage, with few effective treatments available to restore lost function. Induced pluripotent stem cells (iPSCs) have the potential to generate all cell types in vitro and can be generated from a stroke pat