Human Induced Pluripotent Stem Cell (iPSC) Handling Protocols: Maintenance, Expansion, and CryopreservationHuman induced pluripotent stem cells (iPSCs) have emerged as an invaluable resource for basic research, disease modeling, and drug discovery over recent years. Given the numerous advantages of iPS...
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该iPSC (渐冻症病人)hiPSC(ALS) [Human Induced Pluripotent Stem Cell, Amyotrophic Lateral Sclerosis]产品的产品描述查看提供的产品说明书。产品形式 该iPSC (渐冻症病人)hiPSC(ALS) [Human Induced Pluripotent Stem Cell, Amyotrophic Lateral Sclerosis]产品的产品形式查看提供的产品说明书。保存...
Human induced pluripotent stem cell (iPSC)-derived MSCs show greater expandability and therefore offer potential for use in tissue repair therapies. Here we explored the regenerative effects of iPSC-MSCs and the mechanisms by which iPSC-MSCs promote mucosal healing via tumor necrosis factor-伪-...
In this study, a human induced pluripotent stem cell derived-cardiomyocyte (hiPSC-CM)-based platform for modeling ischemia–reperfusion was developed utilizing a system enabling precise control over oxygen concentration and real-time monitoring of the oxygen dynamics as well as iPS-CM functionality. ...
Induced pluripotent stem cell-derived hepatocytes (iPSC-HCs) offer a long-term solution to accessing liver tissue from representative diverse as well as idiosyncratic patient populations and can be sourced indefinitely. iPSC-HCs are currently being evaluated as potential replacements for the existing ...
The cell biology of human neurodegenerative diseases has been difficult to study till recently. The development of human induced pluripotent stem cell (iPSC) models has greatly enhanced our ability to model disease in human cells. Methods have recently been improved, including increasing reprogramming ...
Abbreviations: BMP, bone morphogenic protein; EB, embryoid body; EPO, erythropoietin; FGF, fibroblast growth factor; HC, hydrocortisone; iPSC, induced pluripotent stem cells; IBMX, isobutylmethyl xanthine; IGF, insulin-like growth factor; IL, interleukin; SCF, stem cell factor; TPO, thrombopoietin...
Purpose Defined differentiation of functional RPE cells from human embryonic (hESC) or induced pluripotent stem cells (iPSC) is a prerequisite for their use in individualised disease modelling, drug discovery and transplantation for retinal diseases. In this study we report differentiation of RPE cells...
诱导多能干细胞 (iPSC) 是一种基因重编程的成体细胞,表现出与胚胎干细胞相似的多能干细胞样状态。1虽然这些人工生成的细胞在人体中并不存在,但它们表现出与胚胎干细胞 (ESC) 非常相似的特性;因此,iPSC 是药物发现、细胞治疗和基础研究的宝贵资源。