CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an...
MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes. Sakai,N,Wada,T,Furuichi,K,Shimizu,K,Kokubo,S,Hara,A,Yamahana,J,Okumura,T,Matsushima,K,Yokoyama,H,Kaneko,S. Journal of Leukocyte Biology . 2006Sakai N, Wada T, Furuichi K, et al. MCP-1/CCR2-...
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Here we provide evidence for an evolutionary trade-off between the activity and specificity in human TFs encoded as submaximal dispersion of aromatic residues in their intrinsically disordered protein regions. We identified approximately 500 human TFs that encode short periodic blocks of aromatic residues...
CD14-CHO pro-536 Recombinant Human CD14 CHO derived mCD14 pro-537 Recombinant Mouse CD14 CD1B pro-1267 Recombinant Human CD1B CD2 pro-1337 Recombinant Human CD2 CD2 GST pro-468 Recombinant Human CD2, GST Tag CD23 pro-470 Recombinant Human CD23 CD226 pro-1353 Recombinant Human CD226 CD244 ...
CD14+ monocytes (purity > 98%) were depleted through positive selection using CD14 MicroBeads (Miltenyi Biotec). CD4+ T cells were isolated from the CD14− cell fraction by negative selection (Miltenyi Biotec) and stained with CD4-PerCP/Cy5.5 (clone SK3, 1:200), CD45RA-APC/Cy7 (...
Cells were incubated with monoclonal antibodies to human antigens CD14 (FITC), CD34 (PE), CD45 (PerCP Cy-5.5), and CD133 (APC; Myltenyi Biotec), with respective isotype controls IgG2a (FITC), IgG1 (PE), IgG1 (PerCP Cy-5.5), and IgG1 (APC) (Becton Dickinson), at 4°C for ...
mCD14 pro-537 Recombinant Mouse CD14 CD1B pro-1267 Recombinant Human CD1B CD2 pro-1337 Recombinant Human CD2 CD2 GST pro-468 Recombinant Human CD2, GST Tag CD23 pro-470 Recombinant Human CD23 CD226 pro-1353 Recombinant Human CD226 CD244 pro-1173 Recombinant Human CD244 CD247 pro-1335 Reco...
Both LPS and SAC were potent stimuli of IL-18 protein secretion (P<0.01). LPS-mediated IL-18 gene expression and secretion was CD14-dependent and significantly inhibited by co-incubation of PBMC with neutralizing CD14 antibody (P<0.01). We conclude that LPS-driven IL-18 is dependent on the...
Krenning G, van der Strate BW, Schipper M, van Seijen XJ, Fernandes BC, van Luyn MJ, Harmsen MC (2009) CD34+ cells augment endothelial cell differentiation of CD14+ endothelial progenitor cells in vitro. J Cell Mol Med 13(8B):2521–2533. https://doi.org/10.1111/j.1582-4934.2008.00...