The invention belongs to the field of microbial and animal cell lines, and particularly relates to a human breast cancer cell line MDA-MB-231/08-001 with spontaneous high lung metastasis potentiality and an establishment method thereof. The cells of the cell line are humanized cells that have ...
The phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumor bulk are difficult to study using only primary tumor tissue. We embarked on this study hypothesizing that breast cancer cell lines would contain analogous ...
Differentiation programs are aberrant in cancer cells allowing them to express differentiation markers in addition to their tissue of origin. In the present study, we demonstrate the multi-lineage differentiation potential of breast cancer cell lines to express multiple neuronal/glial lineage-specific mark...
We have examined the expression of several myeloid cell associated antigens, some of which are involved in myelomonocyte adhesion, in seven well characterized human breast cancer cell lines, since common properties of adhesiveness and migration are found in haemopoietic cells and epithelial cancer cells...
breast cancer cell proteinases play in bone degradation we compared the effects of three human breast cancer cell lines, MDA-MB-231, ZR-75-1 and MCF-7 with those of a normal breast epithelial cell line, HME. The cell lines were cultured atop radiolabelled matrices of either mineralized or ...
Low-risk susceptibility alleles in 40 human breast cancer cell lines. BMC Cancer. 2009; 9 :236.Riaz M, Elstrodt F, Hollestelle A, Dehghan A, Klijn JG, Schutte M. Low- risk susceptibility alleles in 40 human breast cancer cell lines. BMC Cancer 2009;9:236....
Introduction The phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumor bulk are difficult to study using only primary tumor tissue. We embarked on this study hypothesizing that breast cancer cell lines would contain...
In the present study we used the human breast cancer cell lines MCF-7 and MDA-MB-231 as model systems to study regulation of lactate flux in cancer cells under normoxic and hypoxic conditions. The experiments revealed that cancer cells increase lactate production and lactate transport capacity ...
Eight human breast cell lines (human mammary epithelial cells, and MCF10A, MCF7, SUM149, SUM159, SUM1315 and MDA.MB.231 cells) were analyzed using flow cytometry for CD44, CD24, and epithelial-specific antigen (ESA) expression. Limiting dilution orthotop
The human breast cancer resistance protein (BCRP/ABCG2), the second member of the G subfamily of the large The ATP-binding cassette (ABC) transporter superfamily, is an ATP-binding cassette (ABC) efflux transporter. BCRP was initially discovered in multidrug resistant breast cancer cell lines. ...