An enrichment analysis of Gene Ontology (GO) biological processes (BPs) showed that the two lethal FUSIL categories (CL and DL) were involved in different types of biological processes (Fig.1b, Supplementary Data1). Whereas the set of CL genes was enriched for nuclear processes (DNA repair, ...
Oldest human DNA reveals lost branch of the human family tree•Dec. 14, 2024, 3:28 AM ET (CNN) human being, a culture-bearingprimateclassified in the genusHomo, especially thespeciesH. sapiens. Human beings are anatomically similar and related to the greatapesbut are distinguished by a mo...
A nomenclature system for the tree of human Y-chromosomal binary haplogroups. Genome Res. 12, 339–348 (2002). de Knijff, P. Messages through bottlenecks: on the combined use of slow and fast evolving polymorphic markers on the human Y chromosome. Am. J. Hum. Genet. 67, 1055–1061 (...
High-throughput DNA sequencing and enhanced culture-based investigations have found bacterial DNA and live bacteria, respectively, in catheterized (bladder) urine deemed culture-negative by the standard urine culture method [1,2,3,4,5,6,7,8,9,10,11,12,13]. The expanded quantitative urine cult...
HSC differentiation is believed to progress through stepwise restriction of lineage potential, a concept that is summarized by the classical tree model of murine hematopoiesis (Spangrude, 1991, Till and McCulloch, 1980). HSC differentiation in human is less well understood than in mouse. Despite ...
Human chorionic gonadotropin (HCG), a hormone produced by cells of the placenta, can be extracted from the urine of pregnant women days after fertilization and thus is used in the early detection of pregnancy. It is also used to stimulate descent of the testicles in… ...
A visit to a home renovation caught the eye of a dentist—and is exciting researchers around the world.
Table S1. Previous single-cell studies; donor characteristics; snRNA-seq and snATAC-seq data and quality control metrics, related to Figures 1 and 5 Table S2. Subcluster membership in major clusters and developmental trajectories; hotspot modules; and IN subcluster investigation, related to Figures...
et al. Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region. Genomics 13, 1209–1230 (1992). Article CAS PubMed Google Scholar Wooster, R. et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 378, 789...
Re-activating quiescent adult epicardium represents a potential therapeutic approach for human cardiac regeneration. However, the exact molecular differences between inactive adult and active fetal epicardium are not known. In this study, we combined fet