HSV-1oral lichen planusprimary herpetic gingivostomatitisrecurrent intraoral herpesRecurrent HSV-1 infection has various clinical features. This case report addresses three differences in the oral clinical mani
Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from signifi
added and included goat anti-rat IgG conjugated with Alexa Fluor 546 (Invitrogen, Eugene, OR), donkey anti-rabbit Alexa Fluor 488 (Jackson ImmunoResearch, West Grove, PA), goat anti-hamster TRITC (Jackson ImmunoResearch) all diluted 1:200 in 0.1% Triton/PBS and incubated overnight at 4 °C...
A high overall prevalence of HSV-1 IgG was observed (97.5%), and in females and males (97.6% and 97.3%, respectively), as shown in Table 1. The distribution of HSV-1 positivity and negativ- ity corresponding to age, where the mean age at infection was 30 years (interquartile range...
A high overall prevalence of HSV-1 IgG was observed (97.5%), and in females and males (97.6% and 97.3%, respectively), as shown in Table 1. The distribution of HSV-1 positivity and negativ- ity corresponding to age, where the mean age at infection was 30 years (interquartile range...
(right) cells.cHeatmap demonstrated the influence of the expression of ISG mRNA with high editing indices on oHSV-treated (MOI = 1, 24 h) 4T1 cells after IFNAR-1 blockade.d4T1 cells were infected with oHSV (MOI = 1, 24 h) and IFNAR-1 blockade, the cellular protein ...
Mouse polyclonal anti-IgG Proteintech Cat# B900620; RRID: AB_2883054 Rabbit monoclonal anti-N6-Methyladenosine Cell Signaling Technology Cat# 56593;RRID: AB_2799515 Anti-mouse IgG, HRP-linked Antibody Cell Signaling Technology Cat# 7076;RRID: AB_330924 Anti-rabbit IgG, HRP-linked Antibody Cell ...
Results of in situ hybridization experiments for the high-affinity receptors of NT-3 have shown that TrkC is expressed in Type I neurons of the postnatal spiral ganglion in rat and guinea pig (13, 14). In normal animals, Type I ganglion cells constitute the vast majority of cochlear neurons...
(Fig. 3c). In contrast to this, microglia mounted response to HSV-1 infection with production of high levels of type I IFN, and this was entirely dependent on STING and cGAS (Fig. 3c,d). Similar data were obtained when we examined IFN-β expression at the messenger RNA (mRNA) levels...
IgG controls showed no signal, indicating the specificity of the assays (data not shown). Lanes 1 and 2: LAT TRE ChIP primers; lanes 3-6: ICP0 promoter primers. (B) Cells were cotransfected with pSG28 and with or without expression vectors of BRG1 or K785R specified in the figure....