To investigate the mechanism of Golgi matrix protein 130(GM130) regulating the antiviral immune response of TLR3 after herpes simplex virus type 1(HSV-1) infection of microglia cells. We explored the regulatory effects of berberine on the immune response
The test had a specificity of 100% and a sensitivity of 100%. The results were assessed using binary outcomes of positive and negative HSV-1 IgG and IgM. The ELISA technique ensured high antigen specificity, which minimized the incidence of false positives due to cross-reactions with anti-HSV...
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HighexpressionofHSV-1glycoproteinGgenefragmentandpurification 系统标签: hsv疱疹高效表达纯化基因片段病毒 论者I 型单纯疱疹病毒 g G 基因片段的 高效表达.纯化 王洁 李越希 张云 !摘要" 目的 获得具有优势抗原表位的 I 型单纯疱疹病毒糖蛋白 G 的表达抗原并纯化鉴定 方法 用 PCR 技术扩增经分析筛选出的 HSV -...
Results Scavenger receptor ligands inhibit HSV-1 infection. Surface epithelial cells are the initial target for viral entry and can activate a potent innate immune response through TLR3 (refs 25–28). Activation of TLR3 increases pro-inflammatory cytokines, antimicrobial peptides and interferons (IF...
Analysis HSV-1 seropositivity Sera that had been banked at − 80 °C were used for serological analysis; serum HSV1-IgG titers were measured using commercially available enzyme immunoassays (ELISA) (IBL International, Hamburg, Germany) in accordance with the manufactures instructions. The assay...
HSV-1oral lichen planusprimary herpetic gingivostomatitisrecurrent intraoral herpesRecurrent HSV-1 infection has various clinical features. This case report addresses three differences in the oral clinical manifestation of HSV-1 with the same high level of IgG titers reaching 200 U/mL. IgG antibody ...
Results are expressed as fold change in band intensities from HSV-1- versus mock-infected samples at the same time point. Data represent the mean values ± s.d. of three separate experiments for each time course. Multiple comparisons by Bonferroni's post-hoc ANOVA test gave the following ...
distribution in terms of high- and low-expressing Ly6G and Ly6C phenotypes. *p < 0.05 comparing the C3 KO to WT mouse CD45+CD11b+Ly6G+Ly6ClowCCR2−CD115−granulocyte/neutrophil phenotype as determined by unpaired, two-tailt-test. The results displayed are from two independent ...
Howsafeissafersex?HighlevelsofHSV-1andHSV-2in femalesexworkersinLondon J.FOX1*,G.P.TAYLOR1,S.DAY2,J.PARRY3ANDH.WARD4 1DepartmentofGenitourinaryMedicineandInfectiousDisease,ImperialCollegeLondon,UK 2DepartmentofAnthropology,Goldsmith’sCollege,UniversityofLondon,UK 3SexuallyTransmittedandBloodborneVirus...