Clearance of HSV-1 antigen following acute ocular infection is hindered in C3 KO mouse corneas. HSV-1-infected WT and C3 KO mice were euthanized by exsanguination at day 7 or day 14 pi. Corneas were surgically removed and processed for immunohistochemistry using anti-HSV-1 and anti-CD45 ...
The immunogenicity of the mixed antigen ISCOMs was evaluated in mice, following administration by the subcutaneous route, by measuring the total and subclass IgG antibody responses. Protection of these animals against challenge with live influenza A/Sichuan virus or live HSV-1, was compared with ...