用强毒HSV-2攻击后,用ΔgD-/+按皮下-阴道内方式免疫的小鼠显示阴道中抗HSV-2gBT-ICD8+T细胞(C)和CD4+T细胞(D)的数目增加。加工阴道组织以提取T细胞并用抗体染色以便流式细胞分析。用(CountBrightTM,Lifetechnologies)进行细胞计数。(*p<0.05;**p<0.01)。发明详述提供一种分离的重组单纯疱疹病毒-2(HSV-2),...
使用重组单纯疱疹病毒2(HSV-2)疫苗载体的免疫的被动转移.pdf,使用重组单纯疱疹病毒2(HSV‑2)疫苗载体、其病毒颗粒、包含其的组合物和疫苗的免疫被动转移的方法。(19)中华人民共和国国家知识产权局 (12)发明专利申请 (10)申请公布号 CN 113727728 A (43)申请公布日 2021.11
According to the manufacturer’s protocol, VUs represent the 10-times quotient of the samples’ optical density (OD) and the OD of a kit-provided cut-off control. VU > 11 is considered positive, while VU < 9 is determined negative. VU values between 9 and 11 are considered equivocal/...
Thus, HSV1 and HSV2 preferentially replicate and establish latency in different populations of sensory neurons (Table 1) [6,7,9,10]. However, these preferred sites of latency only account for about half of the latent sites and it is not clear whether the viruses reactivate from these ...
6 of 16 a 3T3 3T6 1×106 1×105 NS * ** 1×104 1×103 1×102 1×101 24 48 Hours 72 c NS b 3T3 48)hour)MOI)1 3T6 48)hour)MOI)1 d 2.0×106 3T6 MOI 10 1.5×106 3T6 MOI 5 3T6 MOI 1 1.0×106 * 5.0×105 0.0 0 * 9 21 33 45 57 69 Hours FFiigguurree 22.. ...