BTLA抑制剂可以增强TCR信号通路,并恢复T细胞功能,成为肿瘤生物治疗潜在的新靶点。 Fig.1. (A) Interactions around PD1 and HVEM. PD1 belongs to the B7/CD28 (Immunoglobulin) superfamily and delivers negative signals upon binding to its ligands, PD-L1 and PD-L2. Recently, an unexpected interaction ha...
结果显示:在C57BL/6小鼠中可检测到mPD-1+细胞。 在B-hPD-1/hBTLA纯合鼠中,可检测到hPD-1+细胞。 百奥赛图盛产各类基因打靶小鼠,免疫检查点小鼠...有意者欢迎随时咨询订购哦~ 参考文献 [1]Interfering with coinhibitory molecules: BTLA/HVEM as new targets to enhance anti-tumor immunity回复此...
BTLA抑制剂可以增强TCR信号通路,并恢复T细胞功能,成为肿瘤生物治疗潜在的新靶点。 Fig.1. (A) Interactions around PD1 and HVEM. PD1 belongs to the B7/CD28 (Immunoglobulin) superfamily and delivers negative signals upon binding to its ligands, PD-L1 and PD-L2. Recently, an unexpected interaction ha...