primary CNS lymphomaintraocular lymphomavitreoretinal lymphomaSummary The eye is a rare site for the development of malignant lymphoma. Based on cell type and involved intraocular structures, which as a whole represent an immune-privileged site, several subtypes of primary intraocular lymphoma need ...
Areas covered MRI of the total neuroaxis followed by CSF cytomoprhology and flow cytometry are methods of choice when CNS lymphoma (CNSL) is suspected. To reduce the numerous pitfalls of these examinations several aspects should be considered. New CSF biomarkers might be of potential diagnostic ...
One unique clinical presentation is that of iNHL with circulating peripheral blood lymphoma cells with or without splenomegaly, but with minimal to no lymphadenopathy (LAD). This presentation is characteristic of SMZL, but can also be seen in a subset of chronic lymphocytic leukemia/small lymphocytic...
Before receiving TYSABRI, it is important to tell your doctor: If you have a medical condition that can weaken your immune system, such as HIV infection or AIDS, leukemia or lymphoma, organ transplant, or others, or if you have any new or worsening medical problems that have lasted several...
CNS prophylaxis has been incorporated into the sequential JCOG clinical trials and is recommended as a standard of care for acute or lymphoma subtypes treated with either chemotherapy or ZDV/IFN-α. There are no randomized studies in ATL designed specifically to determine which prophylactic strategies...
Tumor-derived exosomal circFARSA mediates M2 macrophage polarization via the PTEN/PI3K/AKT pathway to promote non-small cell lung cancer metastasis. Cancer Treat Res Commun. 2021;28:100412. Article PubMed Google Scholar Hsu Y-L, Hung J-Y, Chang W-A, Jian S-F, Lin Y-S, Pan Y-C, ...
Severe infections in neutropenic patient often progress rapidly leading to life-threatening organ dysfunction requiring admission to the Intensive Care Unit. Management strategies include early adequate appropriate empirical antimicrobial, early admission to ICU to avoid any delay in the diagnostic and therape...
During radiation therapy for brain metastases, ALK TKIs are usually withheld on the days of local therapy with radiation and restarted on the day after radiation is completed in order to minimise the risk of neurotoxicity. No change in dosage is required.28 How I treat CNS disease in ALK ...
Calcium Calmodulin CNS Glioblastoma Stem cells 1. Introduction Glioblastoma (GBM) is the most aggressive primary brain tumor with an extremely bad prognosis. Recurrence after treatment is a major problem with a survival rate for one year ranging about 39.7% [1]. Ideal outcomes are still difficult...
This was done because primary CNS lymphoma is a relatively rare cancer, and it was decided that there was already sufficient knowld about the sadiar treatment, radiotherapy, but that greater information was required about adjuvant chemotherapy. Pw _*es In order to caculate the power or sample ...