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Hypertrophyoccurs when one muscle must work harder to compensate for weakness in another; pseudohypertrophy occurs when muscle tissue is replaced by excessive connective tissue or nonfunctional material (eg, amyloid). Fasciculations(brief, fine, irregular twitches of the muscle visible under t...
To understand why the dexamethasone suppression test (DST) for the diagnosis of depression became widely accepted and later rejected, we reviewed the sequence of publications in the DST literature. To evaluate the events, we developed and applied concepts of a five-phase process that can be used...
Participants were asked to identify with a presented case (video vignette) of an MCI patient and asked whether they would prefer additional diagnostic testing with amyloid PET in this situation. If yes, respondents were asked how much they would be willing to pay for additional diagnostic testing...
Some trials focus on drugs that could halt or slow disease progression. For instance, certain medications target amyloid plaques, protein clusters in the brain thought to play a role in Alzheimer’s. While these treatments aren’t cures, they represent a step toward managing symptom...
Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-beta peptide (x->=41) and tau This invention provides methods useful in aiding in the diagnosis of Alzheimer's disease. The methods involve measuring the amount of amyloid-.beta. peptide (x- >=41) in the cereb...
There is no cure for Alzheimer's, but there are treatments—from cognitive enhancers to non-drug approaches—to help manage it. Learn about the options.
The device, described as a “mesoporous silica nanostructure,” was designed to prevent peptides from forming plaque in the brain, a process believed to be linked to the development of Alzheimer’s disease. The nanostructure is covered in extremely tiny antibody fragments that capture ?-amyloid (...
Trinity researchers have examined the effectiveness of a new blood test which could change the way Alzheimer's disease is identified. The blood test (plasma p-tau217) detects the presence of amyloid plaques that build up in the brain of people with Alzhe
Moreover, in the gamma-treated mice he measured increased diameter of the lymphatic vessels that drain away the fluids and measured increased accumulation of amyloid in cervical lymph nodes, which is the drainage site for that flow. To investigate how this increased fluid flow might be happening,...