Both medications can help treat cognitive symptoms by reducing amyloid plaques in the brain and are administered intravenously (into a vein).6 These treatments are intended to slow neurodegeneration and disease progression. In January 2024, Biogen, the maker of Aduhelm, announced that it would ...
The device, described as a “mesoporous silica nanostructure,” was designed to prevent peptides from forming plaque in the brain, a process believed to be linked to the development of Alzheimer’s disease. The nanostructure is covered in extremely tiny antibody fragments that capture ?-amyloid (...
Researchers wanted to know if a simpleblood testwould be easier and more accurate than alumbar puncture(spinal tap), which currently is the only method to detectamyloid plaques. The lumbar puncture is invasive, and scans are limited in their availability. The use of blood tests has clear advan...
Increased LDL Receptor Lowers Amyloid Plaques via Apolipoprotein E: Study Offers New Insight On How APOE Works in Alzheimer DiseaseAn abstract is unavailable.doi:10.1097/01.NT.0000368610.67574.61ROBINSONRICHARDNeurology Today
Some trials focus on drugs that could halt or slow disease progression. For instance, certain medications target amyloid plaques, protein clusters in the brain thought to play a role in Alzheimer’s. While these treatments aren’t cures, they represent a step toward managing symptom...
reduced inflammation from intermittent fasting can help protect against cognitive decline,as shown in animal research. High levels of insulin and chronic inflammation are risk factors for Alzheimer’s, as they can lead to insulin resistance in the brain and exacerbate the formation of amyloid plaques...
Beta-amyloid buildup forms plaques around brain cells. Tau deposits form twisted fibers called tangles within brain cells. As these proteins accumulate in and around the brain cells, the brain starts to lose its ability to function properly, this leads to loss of brain tissue, and eventually, ...
, a privileged brain-only method of draining and disposing of molecular wastes. This transport system, when healthy, involves shuttling neurotoxic proteins such as amyloid-β out of the brain. On the flip side, an unhealthy system allows amyloid to accumulate into dangerous, mind-robbing plaques....
Alzheimer Disease (AD) is the most common neurodegenerative disorder worldwide, and account for 60% to 70% of all cases of progressive cognitive impairment in elderly patients. At the microscopic level distinctive features of AD are neurons and synapses
Dementia can present differently depending on the individual and their personal history. However, there are a few signs and symptoms to look out for. Living with dementia or caring for someone with this condition can be challenging. By connecting with a therapist, you can learn new coping ...