Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes. The findings are being published today in the scientific ...
How do the "R" groups of amino acids contribute to the 3-D shape of a protein? How is the amino acid analysis of proteins performed? 1. How does an amino acid's sequence in a protein affect its shape and its function? Use types of molecular bonding and structure of individual amino ...
1A). Due to this sequence overlap, the evolution of asORFs would be constrained by the evolutionary selection pressures on the sense ORF. Furthermore, these constraints would be different for asORFs located in the three different frames. We analysed the evolution of asORFs when the sense ORF ...
In the living cell, proteins are efficiently sorted to a whole range of subcellular compartments. In many cases, sorting specificity is mediated by short 'sorting signals' attached either permanently or transiently to the protein. At long last, a fairly coherent picture of the design and function...
but there is a lot to be done before we even start to approach the possibility of large-scale PTM analysis in human samples.” He concludes that “high-resolution methods are the only methods that will survive in the long run. The quest for obtaining full sequence information (which is esp...
How do proteins fold in cells? What are the sequences or structural signals that dictate folding pathways? The new challenge will be to understand ... Rothman,E James - 《Cell》 被引量: 1871发表: 1989年 Fold and function of polypeptide transport-associated domains responsible for delivering un...
CD-HIT (CD-HIT-EST) clusters similar proteins into clusters that meet a user-defined similarity threshold. CD-HIT-2D (CD-HIT-EST-2D) compares 2 datasets and identifies the sequences in db2 that are similar to db1 above a threshold. ...
What is the expressed sequence of DNA that codes for proteins? Explain how the sequence of DNA impacts the function of the gene. Describe how DNA sequences can reveal evolutionary relatedness. True or False: To make a cDNA library, both a DNA polymerase and a reverse transcriptase must be ...
Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it MR Wilkins,JC Sanchez,AA Gooley,... - 《Biotechnology & Genetic Engineering Reviews》 被引量: 0发表: 1996年 The assembly of the export apparatus (YscR,S,T,U,V) of the ...
To produce structural and accessory proteins, members... AO Pasternak,S Wjm,EJ Snijder - 《Journal of General Virology A Federation of European Miorobiological Societies Journal》 被引量: 0发表: 2020年 加载更多研究点推荐 Sequence 站内活动 ...