The models are tested by mutagenesis using an MHC and a TCR mutated to alter conformation changes. The extensive comparisons between theory and experiment provide model validation and testable hypothesis regarding specific conformational changes that control bond profiles, thereby suggesting structural ...
You will need to select the right water model in your :ref:`top` file, either with the ``-water`` flag to :ref:`pdb2gmx <gmx pdb2gmx>`, or by editing your :ref:`top` file appropriately by hand. For information about how to use solvents other than pure water, please see :ref...
Substrate binding (NO3− or NO2−) is required to weaken the electrostatic repulsion and drive the conformational switch. We further identified key residues involved in substrate recognition, binding, exchange, and translocation, and provided a detailed model of the complete exchange process. This...
The models are tested by mutagenesis using an MHC and a TCR mutated to alter conformation changes. The extensive comparisons between theory and experiment provide model validation and testable hypothesis regarding specific conformational changes that control bond profiles, thereby suggesting structural ...
It is thought that they have evolved to play a specific role in defense against animals, pathogens, and various insects, giving advantage in a particular niche [2,3]. One of the most toxic proteins known in nature are plant toxins from the class of ribosome-inactivating proteins. The ...