The main risk factors for AD, referred to as the triad of risk, include age, with most cases occurring after 65, carrying at least one e4 allele of the apolipoprotein (APOE) gene, and biological female sex [4]. Consequently, women represent two-thirds of all AD cases [5, 6], and ...
reuteri NCIMB 30242 per day for nine weeks reduced LDL-cholesterol levels, as well as hs-CRP, apolipoprotein B-100 (apoB-100) (a lipid fraction associated with atherosclerosis development), and fibrinogen levels, and increased vitamin D levels.158,159 Similarly, a yogurt providing 1.4 billion ...
HDL is actually more complex than we once thought. Rather than being a single kind of particle, HDL is is now considered a family of different particles. All HDL contains lipids (fats), cholesterol and proteins (called apolipoproteins), but some types of HDL are spherical while others are ...
Mendelian randomization studies have established that polymorphisms resulting in less ACL associate with a reduction in cardiovascular risk, directly proportional to the degree of lowering of either LDL-C or apolipoprotein (apo) B [19]. This would suggest that ACL inhibition has the potential to be...
[17]. Of note, recent studies also identified apolipoprotein C3 as a signal for alternative inflammasome formation [149]. By uncoupling inflammasome activation from lytic cell death, alternative inflammasome activation consequently provides a platform for sustained inflammatory signaling that may provide ...
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Similar to LDL, an Lp(a) particle also contains one molecule ofapolipoprotein B (apoB). Lipoproteins that promote atherosclerosis (the leading underlying cause of heart disease) are termed atherogenic. ApoB is an essential component of all atherogenic lipoproteins. ...
The potential role of RAGE in the atherogenic process in diabetes has been demonstrated by Park and associates [43]. In the model of atherosclerosis-prone mice due to homozygous deletion of apolipoprotein E (apoE) gene, the induction of diabetes using streptozotocin resulted in atherosclerosis of ...
APOE ε4=Apolipoprotein E ε4 allele; SES=socioeconomic status; TBI=traumatic brain injury; OSA=obstructive sleep apnea; BMI=body mass index; CPAP= continuous positive airway pressure; Early life ↑=ideal to modify early life and onwards. For each MDRF, the classification was made by ...
Congregate evidence suggests that a diet rich in plant-based agents including spices has the ability to prevent most of the chronic diseases. The earliest evidence of the use of spices by humans dates back to 5000 B.C., and till today their biological activities have been extensively studied ...