Kariko has spent her whole life trying to figure out how to use a person's own cells to cure and prevent illness.She focused on mRNA,or messenger RNA,which could be used to instruct cells to make their own medicines,including vaccines(疫苗).In the 1990's,Kariko tried ...
2D, Figure S2). The cumulative length of all the asORFs in the frame 1 was also higher than those in the other two frames (Fig. 2E, Figure S2). This was true for all the seven lines, and also for the set of unique orthologous sequences between all the lines (orthogroups). ...
Sequence of writing Abstract Figure layout Figure legend Material and methods Results Introduction Discussion Abstract Rationale “…remain unknown”; “…To determine…” Summary statement “Here we show…” Body Don’t go into details; don’t use many special terms Significance Must point out, ...
Sequence of writing Abstract Figure layout Figure legend Material and methods Results Introduction Discussion Abstract Rationale “…remain unknown”; “…To determine…” Summary statement “Here we show…” Body Don’t go into details; don’t use many special terms Significance Must point out, ...
RNA molecules can fold into intricate shapes that can provide an additional layer of control of gene expression beyond that of their sequence. In this Review, we discuss the current mechanistic understanding of structures in 5′ untranslated regions (UTRs) of eukaryotic mRNAs and the emerging metho...
aThe PRKC ε mRNA contains a 3 ′ -UTR sequence that is partially complementary to miR-205(Figure 1 A). 正在翻译,请等待... [translate] a这是多么让人开心的呀 This is how happy[translate] a我在这里不仅欣赏到了各种各样的园艺和建筑,而且还了解了西安的历史和文化。 Not only I appreciated ...
I don't believe that this can be accomplished using ExecuteNonQuery. Below is an link that demonstrates how to use the SqlInfoMessageEventHandler delegate to provide progress information.http://geekswithblogs.net/mrnat/archive/2004/09/20/11431.aspxPaul ~~~ Microsoft MVP (Visual Basic)Monday...
To persist, cells must multiply only in response to specific signals, they must have mechanisms to detect errors in the dupli- cation process, and they must establish a defined sequence for the events of duplication, so that DNA replication, for example, always precedes cell division. In ...
et al. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature 413, 852–856 (2001). Article CAS PubMed Google Scholar Champion, K. & Higgins, N. P. Growth rate toxicity phenotypes and homeostatic supercoil control differentiate Escherichia coli from Salmonella enterica ...
If the variant also affects a functionally important mitochondrial function and is heteroplasmic, this further increases the likelihood that the mutation is contributing to the disease.21 On the basis of this logic, we have developed a database of several thousand mtDNA sequences that encompasses ...