Advanced organoid models can be interconnected, using microfluidics and organ-on-a-chip technologies, to recapitulate physiological interactions in the body. This connectivity will enhance multi-omics’ ability to reveal not only the systemic interactions in diseases, but also the initiating events that ...
In preferred embodiments, the method comprises comparing the length and at least part of the nucleotide sequence of the PCR products to expected values determined from a database of nucleotide sequences. The method can identify changes in expression of mRNA associated with the administration of ...
Before they can sequence DNA or alter it through genetic engineering, scientists must first isolate it. This might seem like a difficult task, since cells contain a wide variety of other compounds like proteins, fats, sugars and small molecules. Fortunately, biologists can make use of DNA's ch...
We discuss known 5′ UTR RNA structures and how new structure probing technologies coupled with prospective validation, particularly compensatory mutagenesis, are likely to identify classes of structured RNA elements that shape post-transcriptional control of gene expression and the development of ...
These studies raise new questions about how to conceptualize RNA folding and how to identify new mechanisms for which RNA dynamics are a core component. Here we pose three prominent questions for the field that we believe are at the forefront of our knowledge of the importance of RNA folding ...
Cell line screening and selection strategies can be designed to maximize the chance of selecting a high-producing cell line. Lonza uses the Beacon® optofluidic system to screen thousands of clones at the single-cell stage to identify those most suitable for progression. ...
Identify and describe the process whereby RNA is created from a strand of DNA. Why is DNA stable but RNA is not? How does DNA replication initiate? What are the functions of RNA? How is RNA converted into cDNA? How did RNA polymerase come into existence? Was it due to a mutation in ...
Biometrics uses unique features,like iris recognition, to identify you. Photo courtesy Iridian Technologies How Biometric Information is Encoded Biometric systems can seem complicated, but they all use the same three steps: Enrollment: The first time you use a biometric system, it records basic infor...
Provide a detailed account of a method that can identify sequences of DNA based on the principle of hybridization and discuss its applications Explain the steps to dideoxy sequencing. How does genomics rely on DNA sequencing? Explain the process of RNA being translate...
Identify sequencing panels or microarrays that target your genes of interest. Search panels by gene, or find genotyping arrays by genomic location, variant ID, or species. Find the Right Product Featured Products NextSeq 2000 System Groundbreaking benchtop sequencers allow you to explore new discoverie...