A synthetic DNA enzyme catalyses the formation of a native phosphodiester bond between two RNA fragments, but the molecular details of the mechanism remained elusive. Research using computational and biochemical approaches now suggests that the DNA enzyme recruits two magnesium ions to assist in the ...
Because most of the intergenic DNA has no known functions, these DNAs are known as junk or selfish DNA.Furthermore, not all genes code for proteins: only genes that are transcribed into mRNA code for proteins. Some genes are transcribed into other types of RNA, which directly participate in...
Transcription is a process where the DNA converts into RNA. Enzymes used in the transcription is RNA polymerase which assembles the nucleotide in RNA by using DNA as a template. In prokaryotes the transcription takes place in three steps I.e. initiation, elongation, and termination. In eukaryot...
Transfer RNAs (tRNA) are the RNAs that “read” the genetic code and translate it into a sequence ofamino acidsto make a protein. The addition of a chemical tag—a methyl sulfur group—to a particular location on some tRNAs improves their ability to translate messenger RNA into prote...
The movement of genetic information in cells from DNA to messenger RNA to protein is described by the central dogma in the field of molecular biology. According to the idea, genes dictate the sequence of mRNA molecules, which determines the sequence of proteins....
Changes in the DNA of cells in multicellular organisms produce variations in the characteristics of a species. Over long periods of time, natural selection acts on these variations to evolve or change the species. The presence or absence of DNA evidence at a crime scene could mean the difference...
et al. Insight into the catalytic mechanism of DNA polymerase β: structures of intermediate complexes. Biochemistry 40, 5368–5375 (2001). The authors of this study show that it is metal B (in this case Cr(III)dNTP) alone that, in addition to inducing rapid conformational change, also ...
COVID-19 is a reminder of their destructive power, but they’re crucial to humans’ development and survival.
For text, it means a written or printed representation of something. For music, it means an arrangement of a piece of music. And, in biochemistry, transcription refers to the genetic information of DNA being copied onto a new strand of RNA. ...
This is usually quoted in terms of ‘fold change’, e.g., if the treated sample produces twice as much mRNA as the untreated sample, the result is a ‘fold change’ of 2. Variations in the quantity of DNA produced in a...