Therapeutic Jurisprudence: How Judges Operate within Problem-Solving CourtsViglione, JillPortillo, ShannonRudes, DanielleNelson, MatthewTaxman, Faye S
To arrive at a school's rank in each of the 51 subjects, subject scores were calculated using a combination of weights and z-scores for each of a given subject's ranking indicators. In statistics, a z-score is a standardized score that indicates how many standard deviations a data point ...
However, it is important to note that the frailty index calculated for the SMART studies, which is a complementary means to the p value for the interpretation of the results of the clinical trials, was very low. This observation suggesting a low robustness of the results [55]. But frailty ...
Endometriosis is a chronic, estrogen-dependent, benign condition, affecting 10–15% of women of reproductive age. It is associated with a prevalence of sexual dysfunction that is nearly twice as high as that seen in women with other benign gynecological
When outdoors, always wear sunscreen with anSPF ratingof 15 or higher. This allows enough ultraviolet (UV) radiation to penetrate the skin to have a therapeutic effect, but not enough to cause burning. There is some evidence that the zinc oxide used in some mineral sunscreens may bebeneficial...
Argollo, M., Kotze, P.G., Kakkadasam, P.et al.Optimizing biologic therapy in IBD: how essential is therapeutic drug monitoring?.Nat Rev Gastroenterol Hepatol17, 702–710 (2020). https://doi.org/10.1038/s41575-020-0352-2 Download citation ...
Looking for treatment-by-subset interaction on a right-censored outcome based on observational data using propensity-score (PS) modeling is of interest. However, there are still issues regarding its implementation, notably when the subsets are very imbal
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in preclinical models and emerging evidence in humans have established the crucial roles of the innate and adaptive immune systems in driving atherosclerosis-associated chronic inflammation in arterial blood vessels. New te...
Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 26, 577–590 (2014). Article CAS PubMed PubMed Central Google Scholar Zouridis, H. et al. Methylation subtypes and large-scale epigenetic alterations in gastric cancer. Sci Transl Med. 4, ...
Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide. Most therapeutic approaches target traditional risk factors but ignore the fundamental role of the immune system. This is a huge unmet need. Recent evidence indica