Define therapeutic index. therapeutic index synonyms, therapeutic index pronunciation, therapeutic index translation, English dictionary definition of therapeutic index. n. The ratio between the toxic dose and the therapeutic dose of a drug, used as a me
divided by the effective concentration, expressed as TC50/EC50, a point at which 50% of Pts have a toxic reaction to the drug being monitored; the lower the therapeutic index, the more difficult it is to titrate a drug's dose in a Pt and the more critical it is that the drug be mo...
Share the Definition of therapeutic index on Twitter Twitter Medical Definition therapeutic index noun : a measure of the relative desirability of a drug for the attaining of a particular medical end that is usually expressed as the ratio of the largest dose producing no toxic symptoms to the...
therapeutic index (redirected fromtherapeutic ratio) Medical n. The ratio between the toxic dose and the therapeutic dose of a drug, used as a measure of the relative safety of the drug for a particular treatment. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright...
Therapeutic index, margin of safety that exists between the dose of a drug that produces the desired effect and the dose that produces unwanted side effects. This relationship is defined as the ratio LD50:ED50. In general, the narrower this margin, the m
___ is any of a group of narrow-spectrum antibiotics that are synthesized from molds and can be used to alleviate a sore throat. Medications that have a narrow therapeutic index need to be monitored since these are only safe and effective within a ___ ___. Patients experiencing ...
The importance of local criteria in the diagnosis of metabolic syndrome in Saudi Arabia The clustering of risk factors predisposing an individual to cardiovascular morbidity and mortality are usually referred to as the 'metabolic syndrome' (MS... SM Bahijri,RMA Raddadi - 《Therapeutic Advances in ...
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, ...
It is a disabling illness that alters patients' quality of life and causes an increase in the use of health resources [2–6]. It is important to define the therapeutic objectives for MD [7], and more experts are claiming that reaching remission should be the main objective since residual ...
According to the cited study, the REM Sleep Atonia Index, introduced in [18], proves to be the most effective for the detection of RSWA. A step forward in automatic sleep analysis has been achieved through Machine Learning (ML) techniques. Automatic classification of sleep disorders has been ...