KARLEN S,MORDINOV VA,SANDERSON CJ.How is expression of the interleukin-5 gene regulated?. Immunology and Cell Biology . 1996KARLEN, S., MORDVINOV, V.A. & SANDERSON, C.J. (1996). How is expression of the interleukin-5 gene regulated? Immunol. Cell Biol., 74, 218 ± 223.Karlen S,...
Gene expression is a tightly regulated process that allows a cell to respond to its changing environment. It enables information stored in our DNA to flow within a complex biological system. Without gene expression, a cell would not exist. Unfortunately, according to Ghorbani, a Ph.D. candidate...
How have gene frequencies changed in populations over time? Why did this occur? Gene Frequency: Gene frequency, also known as allele frequency, is the proportion of the population that has that allele at a certain locus. It can also be thought of as the proportion of organisms ...
How is the eukaryotic DNA packaged? Explain. Cell Nucleus The nucleus is a cellular organelle in most cell types that consists of a nuclear envelope in addition to a double-membrane separating it from the intracellular space. The main purpose of the nucleus is to store and protect the cell'...
The tumour suppressor gene TP53 is mutated in ~50% of human cancers. In addition to its function in tumour suppression, p53 also plays a major role in the response of malignant as well as nontransformed cells to many anticancer therapeutics, particularly
CRISPR has ignited a revolution and has quickly become a standard laboratory tool for gene editing. As the adoption of CRISPR accelerates worldwide, up-to-date knowledge of the basics of CRISPR is essential for anyone in the field. From target identification studies to the recent breakthroughs in...
"Surprisingly, we have revealed an entirely new mechanism through which hemoglobin gene expression is regulated by stress. An intracellular signal, essential for coping with stress, is absolutely necessary to allow for hemoglobin production. That stress signal is activated by the hemoglobin gene itself...
and possibly other co-factors in the process, by the synaptic signals they receive. It will also be interesting to test, which neuronal functions are supported by the Gα12/13-coupling LPHN3 and how their expression is controlled. Ultimately, alternative splicing ofLphn3transcripts may impart ch...
Neuronal migration is a highly dynamic process that is essential for the normal development and function of the mammalian brain. The migration process is regulated by cell-extrinsic signaling pathways and cell-intrinsic regulation and implicates numerous molecules that synergistically guide neuron motility....
In this context, miR-509-3p, miR-204-5p, and miR-211-5p are rapidly upregulated in response to short-term BRAFi treatment [63,64]. miR-204-5p and miR-211-5p whose expression is induced by the transcription factors signal transducer and activator of transcription 3 (STAT3) and ...