miRNAs (microRNAs) are short non-coding RNAs that regulate gene expression post-transcriptionally. They generally bind to the 3'-UTR (untranslated region) of their target mRNAs and repress protein production by destabilizing the mRNA and translational silencing. The exact mechanism of miRNA-mediated ...
miRNAs (microRNAs) are short non-coding RNAs that regulate gene expression post-transcriptionally. They generally bind to the 3'-UTR (untranslated region) of their target mRNAs and repress protein production by destabilizing the mRNA and translational silencing. The exact mechanism of miRNA-mediated ...
The researchers found that once inside the nucleus, influenza A hijacks the RNA exosome, an essential protein complex that degrades RNA as a way to regulate gene expression. The flu pathogen needs extra RNA to start the replication process so it steals these molecules from the hijacked exosome...
Explain how small RNA (sRNAs) molecules can regulate the translation of a piece of mRNA. Describe the process of gene expression, from gene to protein, and how a gene affects the phenotype expressed by an organism. Would a double-stranded RNA derived from an intron be able to...
How can the expression of the gene of interest be ensured? Answer and Explanation: If you're trying to make an engineered bacterium express a gene, you normally put the gene under the control of an inducible promoter. The promoter acts as an on/off switch. It is a segment of DNA i...
acould effectively introduce miRNA into cells without transfection agents, regulate target gene expression, and exert the miRNA specific phenotype. 能有效地介绍miRNA入细胞,不用transfection代理,调控目标基因表达和施加miRNA具体表现型。[translate] a跟进会议全过程 Follows up the conference entire process[transl...
NMD thereby contributes to the elimination of aberrant mRNAs, improving the fidelity of gene expression, but also serves to regulate gene expression at the post-transcriptional level. Here we discuss recent evidence as to how and where mRNAs targeted to NMD are degraded in human cells. We ...
• TGF-β superfamily members regulate early embryonic development. • Smads control expression of both self-renewal and differentiation genes. • Smad transcriptional activity is regulated by post-translational modifications. • Smads collaborate with cofactors on chromatin to regulate transcription. ...
Production of ROS in the extracellular space, the apoplast, can influence their generation in the chloroplast and both can regulate nuclear gene expression. In spite of existing information on these signaling events, we can still barely grasp the mechanisms of ROS signaling and communication between ...
Drug watchdog wins right to regulate controversial therapies. Cyranoski,David - 《Nature》 被引量: 23发表: 2012年 Tech news: stem cells for modeling and curing disease. Freya Leask explores developments in cell culture and stem cell research that are revolutionizing how diseases are studied and ...