How does replacing a gene's promoter with a stronger promoter affect the gene expression of the gene? Describe some different methods that can be used to turn off gene expression. What does no gene flow mean? When does a cell regulate gene expres...
Fig. 1. Post-transcriptional control of gene expression. It comprises a complex regulatory network that contributes to cell-type and organism specific gene expression patterns. The pre-mRNA has to go through some modifications to become a mature mRNA molecule that can leave the nucleus and...
MicroRNAs (miRNAs) — approximately 21-nucleotide-long, genome-encoded RNAs — have emerged as key regulators of gene expression in eukaryotes. miRNAs represent just one class of small RNA regulators, the others being small interfering RNAs (siRNAs) and PIWI-associated RNAs (piRNAs), all of which...
The outcome of this interaction can depend on the degree of sequence complementarity and the specific Argonaute present in the RISC complex, but destabilization of the mRNA and subsequent degradation is likely. Full size image miRs act as major components of an integrated gene expression regulatory ...
Most efforts have focused on unravelling mechanisms controlling the level of transcription and have yielded many answers. Moreover, a multitude of reports have demonstrated the existence of additional regulatory mechanisms which modulate gene expression post-transcriptionally, including mRNA elongation and ...
A method in which one protein is fused to the GAL4 activation domain and the other to the GAL4 DNA-binding domain, and both fusion proteins are introduced into yeast. Expression of a GAL4-regulated reporter gene indicates that the two proteins physically interact. ...
Gene regulation is the controlling of gene expression (turning off or on) in a segment of DNA which predetermines the trait of organisms by taking...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
3. Mechanisms of regulation of gene expression and NSC identity 4. NSC quiescence and activation. Challenges and opportunities 5. Cell type specific targets for molecular intervention 6. Genetic strategies to target quiescent and activated hippocampal NSCs specifically 7. Gene targeting in quiescent and...
Gene regulation or gene expression can be measured using techniques such as western blot and Enzyme-linked immunosorbent assay or ELISA. These...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your toug...
Thematic ReviewA STAR for the ages: a 30-year historical perspective of the role of transcription factors in the regulation of steroidogenic acute regulatory gene expression Author links open overlay panelRobert S Viger 1 2, Marie France Bouchard 1, Jacques J Tremblay 1 2Show more Add to ...