When ossification occurs, the cartilage begins to calcify; that is, layers of calcium and phosphate salts begin to accumulate on the cartilage cells. These cells, surrounded by minerals, die off. This leaves small pockets of separation in the soon-to-be-bone cartilage, and tiny blood vessels ...
Describe the process of endochondral ossification, including bone lengthening. Explain the structure of an irregular bone. What is bone remodeling and why does it occur? Explain the types of bone cells. How to determine the age of a human skeleton?
1. What is Calcification? 2. What is Ossification? How does meningitis affect the brain? How might the bones tell an expert that person is an elderly of 70 years? Explain the difference in the healing speed of bone versus cartilage injury. ...
Does side bone cause lameness? Lameness, primarily associated with sidebones,is rarely seenand if lameness occurs it is usually caused by complicating features, e.g., when the ossification becomes advanced and the growing sidebones press on adjacent sensitive hoof structures and deform the foot. W...
transcription factors that drive VSMCs ossification and molecules that promote VSMCs senescence can be directly inhibited, or the osteogenic genes can be indirectly regulated by miRNAs. Animal studies have demonstrated the feasibility of these approaches, but more evidence is needed before clinical use...
by the sample preparation. However, this limitation does not change the conclusion that normal dynamic loading produces cell death around the cartilage lesions. Ongoing studies focus on the quantification of cell viability results and it will be part of a future investigation. Third, tissue crack ...
While the proximal limb bones are normal in appearance and ossification, some of the distal elements, such as the phalanxes, are missing and others are fused. Other notable skeletal abnormalities include a partially split sternum, fused vertebrae and severe truncation of the skull. Yet, the most...
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Osteoblasts and osteoclasts are cells that work to build and repair bones at the molecular level. Learn more about osteoblasts and osteoclasts, growth plates and bone development, and changes that occur through the processes of ossification and remodeling or repairing of bones. Related...
Describe the process of endochondral ossification, including bone lengthening. What is rickets? What causes it and how does it affect the body? Explain the importance of calcium during a muscle contraction. Describe how alveolar surface tension, c...