Reactive bone formation may then occur farther away from the cartilage abnormality in order to compensate for the localized bone loss. Applying the same methodology, Lindsey and colleagues found that cartilage loss in the medial compartment directly correlated to bone formation in the medial chondyle,...
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While the long-term use of some bisphosphonates does have some side-effects on Earth, such as atypical femoral fractures and osteonecrosis of the jaw, perhaps astronauts will only have to take the drugs in microgravity, and the bone loss on the Moon (1/6 g) or on Mars (1/3 g) will ...