Around the time of birth a secondary centre ofossificationoccurs in the centre of each end of a long bone. These new centres of ossification are responsible for the ossification of the ends of the bones; ossification proceeds from the centre towards the periphery. After the secondary centres of...
This indicates that in this phase most proteoglycans have been degraded, a process which occurs during endochondral ossification. Figures 2E and 2F demonstrate all stages of endochondral ossification in the same pellet, cartilage degradation, blood vessel invasion and bone and marrow formation. Figure ...