Nicosia G., Cutello V., Pavone M., Narzisi G., Sorace G.: "How to Escape Traps using Clonal Selection Algorithms", The First International Conference on Infor- matics in Control, Automation and Robotics (ICINCO) INSTICC Press, Vol. 1, pp. 322-326, (2004)....
The selection of these thrombopoietic agents mainly depends on drug availability, patient-preferred administration form, and anticipated adherence. Furthermore, failing one thrombopoietic agent does not preclude the use of another, as there is accumulating evidence supporting TPO-RA agent switching due ...
The immune system is a complex network of specialized cells that work in concert to protect against invading pathogens and tissue damage. Imbalances in this network often result in excessive or absent immune responses leading to allergies, autoimmune dis
However, the fact that Vγ5/Vδ1 and Vγ6/Vδ1 TCR sequences are present at the DNA level in the foetal thymus of TCRδ−/− mice suggests that the corresponding TCR rearrangements are not necessarily a result of clonal thymic selection [26]. Other cells in the thymus, such as ...
On the basis of a combination of Darwinian theory and the concept of multi-step tumor progres- sion, tumorigenesis is now understood as a succession of clonal expansions.8,9 Selection of cells endowed with advantageous traits requires a large number of cells. However, single-step tumorigen- ...
Human airway epithelial (HAE) cellular models are widely used in applicative studies of the airway physiology and disease. In vitro expanded and differentiated primary HAE cells collected from patients seem to be an accurate model of human airway, offeri
57 It is within GCs where SHM and purifying selection produce the higher affinity B-cell clones that form the memory compartments of humoral immunity.57,58 Significantly, affinity maturation in GCs does not represent an intrinsic requirement for BCR signal strength but rather a local, Darwinian ...
How many years does it take to grow a pawpaw tree from seed to fruit? Your pawpaw trees may produce their first fruit in their fourth year under ideal conditions. However, it’s more likely to be year 5-6. Pawpaw flower pollination: ...
However, although IFN- γ is clearly Viral attenuated vaccines such as measles, mumps, rubella, varicella, an essential element of the protective response, the total amount of polio or yellow fever vaccines are considered to be inducers of life- IFN-γ produced does not necessarily reflect the ...
To show the possible advantages of this approach, we reanalysed two published datasets to answer two questions: (a) does considering interactions between traits by using BRTs result in a higher predictive ability as compared to linear models? and (b) can one use BRTs to identify distinct ...