However, to date numerical simulations are limited to the effect of a single particle and to membranes of small size [29, 30]. The ESCRT machinery and budding The ESCRT machinery is composed of five different complexes, ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III and VPS4, which assemble ...
Chromosomes themselves direct the formation of multiple active MTOCs that later assemble the meiotic spindle. Because the distance of action of microtubules is limited (they can effectively bind to chromosomes only in cells with a diameter not exceeding 30 µm), the positioning of chromosomes is ...