Meanwhile, in obese patients, dietary weight loss intervention alters gut microbiota and decreases circulating succinate concentration [102]. Nevertheless, the results from studies investigating the effects of succinate on appetite-related signaling are inconsistent. One series of studies suggested that ...
Growing evidence suggests that the gut microbiome is an important contributor to metabolic diseases. Alterations in microbial communities are associated with changes in lipid metabolism, glucose homeostasis, intestinal barrier functions, and chronic inflammation, all of which can lead to metabolic disorders....
Existing literature is inconclusive about effect sizes of maternal legacy vs. host genotype. The vendor and genetic background, in terms of host genotype, seem to influence murine gut microbiota [33]. Nevertheless, studies using embryo transplantation and litter cross-fostering in mouse rearing and ...
Existing literature is inconclusive about effect sizes of maternal legacy vs. host genotype. The vendor and genetic background, in terms of host genotype, seem to influence murine gut microbiota [33]. Nevertheless, studies using embryo transplantation and litter cross-fostering in mouse rearing and ...
A strong association between exposure to the common harmful algal bloom toxin microcystin and the altered host gut microbiome has been shown. We tested the hypothesis that prior exposure to the cyanotoxin microcystin-LR may alter the host resistome. We s
Gut microbiota play a critical role in orchestrating metabolic homeostasis of the host. However, the crosstalk between host and microbial symbionts in small mammals are rarely illustrated. We used male Brandt’s voles (Lasiopodomys brandtii) to test the
Worthington JJ, Samuelson LC, Grencis RK, McLaughlin JT (2013) Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion. PLoS Pathog 9: Available: http://www.plospathogens.org/article/info%3Adoi%2F10.1371% 1372Fjournal.pp...
microbiota across three mucosal tissues (skin, gill, and gut) in Atlantic salmon receiving a control diet or diets supplemented with mannan-oligosaccharides, coconut oil, or both. Dietary impacts on mucosal immunity were further evaluated by experimental ectoparasitic sea lice (Lepeophtheirus salmonis)...
A benign helminth alters the host immune system and the gut microbiota in a rat model system. PLoS ONE 2017, 12, e0182205. [CrossRef] [PubMed] 68. Neumann, M.; Goderska, K.; Grajek, K.; Grajek, W. The in vitro models of gastrointestinal tract to study bioavailability of nutriments...
Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans. Cell 2019;178:1313–3. Article CAS PubMed PubMed Central Google Scholar Macpherson AJ. Do the microbiota influence vaccines and protective immunity to pathogens? Issues of sovereignty, federalism, and points-testing...