Growing evidence suggests the implication of the gut microbiota in various facets of health and disease. In this review, the focus is put on microbiota-host molecular cross-talk at the gut epithelial level with special emphasis on two defense systems: intestinal alkaline phosphatase(IAP) and ...
The gut microbiota has been implicated in a range of diseases. This Review describes current understanding of probiotics and prebiotics as a means to manage the microbiota to improve host health, including mechanisms of actions and potential for clinical use. ...
G. et al. Bacteria as vitamin suppliers to their host: a gut microbiota perspective. Curr. Opin. Biotechnol. 24, 160–168 (2013). Article CAS Google Scholar Levy, M. et al. Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling. Cell ...
The gut microbiome is closely associated with health status, and any microbiota dysbiosis could considerably impact the host’s health. In addition, many active consortium projects have generated many reference datasets available for large-scale retrospective research. However, a comprehensive monitoring fr...
Probiotics, gut microbiota, and their influence on host health and disease. Mol Nutr Food Res. 2017;61(1):1600240. Article Google Scholar Lee CY, Dillard LR, Papin JA, Arnold KB. New perspectives into the vaginal microbiome with systems biology. Trends in Microbiology. 2023;31(4):356-68...
Surveillance of host–microbiota interactions. New tools and technological advances have tremendously advanced our understanding of complex microbial communities and their interactions with a host over time, in relation to diet and lifestyle changes, and in health and disease. However, there is...
Growing evidence suggests the implication of the gut microbiota in various facets of health and disease. In this review, the focus is put on microbiota-host molecular cross-talk at the gut epithelial level with special emphasis on two defense systems: intestinal alkaline phosphatase (IAP) and indu...
host's fitness, phenotype, and health.2 Box 1 ### Glossary RETURN TO TEXT Twin studies have shown that, although there is a heritable component to gut microbiota, environmental factors related to diet, drugs, and anthropometric measures are larger determinants of microbiota composition.45 Gut 鈥...
R. et al. The gut microbiota and host health: a new clinical frontier. Gut 65, 330–339 (2016). PubMed Google Scholar Moran, C. & Shanahan, F. Editorial: probiotics and IBS — where are we now? Aliment. Pharmacol. Ther. 40, 318 (2014). CAS PubMed Google Scholar Pinn, D. ...
Although numerous reports link a decreased diversity of the gut microbiota to a declined health status, to date no mechanistic motivation for this exists. Here, we show by applying first principles basic graph theory on small networks that higher diversi