Definition Homeobox genes encode transcription factors that are characterized by the presence of a homeobox. This domain forms three α–helical regions, one of which is involved in sequence specific DNA binding. The name "homeobox" derives from findings that mutations in some of these genes lead ...
Here we demonstrate that the 2C-specific transcription factor double homeobox protein (DUX) mediates an essential negative feedback loop by inducing the expression of DUXBL to promote this silencing. We show that DUXBL gains accessibility to DUX-bound regions specifically upon DUX expression. ...
A total of 914 transcription factors were identified in theA. leiigenome. Transcription factor superfamily members were categorized into 45 different classes according to the functional domain characteristics (Supplementary Table8). After the “zinc finger” transcription factor type, “homeobox” was the...
The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma Geerts, The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma, Exp. Cell Res. ... I Revet,G ...
纳米抗体 英文名字 Nanog Antibody,Homeobox transcription factor Nanog,Homeobox protein nanog,hNanog 供应商 Biovision 产品货号 3165-100 产品报价 ￥已停产 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868....
The CDX2 homeobox transcription factor plays key roles in intestinal development and homeostasis. CDX2 is downregulated during colorectal carcinogenesis, whereas overexpression of CDX2 results in growth inhibition and differentiation of colon carcinoma and intestinal cells. However, the means by which CDX...
Altered enteric expression of the homeobox transcription factor Phox2b in patients with diverticular diseaseDiverticular disease, enteric neuropathy, enteric neurons, enteric glial cells, phox2b, Ret, TH, S100βDiverticular disease, a major gastrointestinal disorder, is associated with modifications of the...
针对Caudal Type Homeobox Transcription Factor 2 (CDX2) BioAssay ELISA Kit (Human)该产品的特点优势,欢迎查阅官网提供的产品说明书。保存建议 建议收到Caudal Type Homeobox Transcription Factor 2 (CDX2) BioAssay ELISA Kit (Human)产品后将其置于4°C/-20°C保存。其他...
Previously, we observed expression of the homeobox transcription factor Prox1 in neuroectodermal embryonic tissues. Besides essential functions during embryonic development, Prox1 has been implicated in both progression and suppression of malignancies. Here, we show that Prox1 is expressed in embryonic sym...
Homeobox Transcription Factor Prox1 in Sympathetic Ganglia of Vertebrate Embryos: Correlation With Human Stage 4s Neuroblastoma JU¨ RGEN BECKER, BAIGANG WANG, HELENA PAVLAKOVIC, KERSTIN BUTTLER, AND JO¨ RG WILTING Department of Anatomy and Cell Biology, University Medicine Goettingen, 37075 ...