Definition Homeobox genes encode transcription factors that are characterized by the presence of a homeobox. This domain forms three α–helical regions, one of which is involved in sequence specific DNA binding. The name "homeobox" derives from findings that mutations in some of these genes lead ...
A total of 914 transcription factors were identified in theA. leiigenome. Transcription factor superfamily members were categorized into 45 different classes according to the functional domain characteristics (Supplementary Table8). After the “zinc finger” transcription factor type, “homeobox” was the...
et al. The homeobox transcription factor DUXBL controls exit from totipotency. Nat Genet 56, 697–709 (2024). https://doi.org/10.1038/s41588-024-01692-z Download citation Received18 November 2022 Accepted16 February 2024 Published20 March 2024 Issue DateApril 2024 DOIhttps://doi.org/10.1038...
DUXO, a novel double homeobox transcription factor, is a regulator of the gastrula organizer in human embryonic stem cells 来自 国家科技图书文献中心 喜欢 0 阅读量: 173 作者:N Sharon,I Mor,E Zahavi,N Benvenisty 摘要: We analyzed previously isolated human organizer cells derived from hESCs. ...
The CDX2 homeobox transcription factor plays key roles in intestinal development and homeostasis. CDX2 is downregulated during colorectal carcinogenesis, whereas overexpression of CDX2 results in growth inhibition and differentiation of colon carcinoma and intestinal cells. However, the means by which CDX...
Homeobox genes and down-stream transcription factor PPARgamma in normal and pathological human placental development Murthi P, Kalionis B, Cocquebert M, Rajaraman G, Chui A, Keogh RJ, Evain-Brion D, Fournier T (2013) Homeobox genes and down-stream transcription factor PPARγ in normal and pat...
(2013). The transcription factor paired-related homeobox 1 (Prrx1) in- hibits adipogenesis by activating transforming growth factor-b (TGFb) signaling. J. Biol. Chem. 288, 3036-3047.Du B, Cawthorn WP, Su A, Doucette CR, Yao Y, Hemati N, et al. The transcription factor paired-related...
Pepper SUMO E3 ligase CaDSIZ1 enhances drought tolerance by stabilizing the transcription factor CaDRHB1 2022, New Phytologist Genome-Wide Analysis of KNOX Transcription Factors and Expression Pattern of Dwarf-Related KNOX Genes in Pear 2022, Frontiers in Plant Science Differential Functions of Pepper ...
Seedless grapes are of considerable importance for the raisin and table grape industries. Previous transcriptome analyses of seed development in grape revealed that genes encoding homeobox transcription factors were differentially regulated in seedless c
Previously, we observed expression of the homeobox transcription factor Prox1 in neuroectodermal embryonic tissues. Besides essential functions during embryonic development, Prox1 has been implicated in both progression and suppression of malignancies. Here, we show that Prox1 is expressed in embryonic sym...